Anemia Cases Flashcards

1
Q

Signs and symptoms of anemia

A

fatigue, exercise intolerance, rapid heartbeat, pallor, tachycardia, systolic murmur, edema

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2
Q

Main two considerations when diagnosing anemia

A

are we not making enough blood? are we losing blood?

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3
Q

What do reticulocytes in PB indicate?

A

compensatory production by bone marrow

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4
Q

Anisocytosis

A

increased red cell distribution width

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5
Q

Clinical presentation of iron deficiency anemia

A

tired, weight loss, onychoschizia, pica, conjunctival pallor, cheilosis

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6
Q

Lab indications that iron is low

A

low serum iron, low serum ferritin, low transferrin (percent of stores)

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7
Q

Indications that body is compensating/waiting for iron

A

increased TIBC, Increased transferrin receptor

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8
Q

When a patient presents with iron deficiency anemia, what would prompt an eval for a GI bleed

A

male patients, postmenopausal females

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9
Q

Three important physiological changes that can result from anemia of acute blood loss?

A

Hypovolemia, MI, renal failure

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10
Q

Lab values for uncompensated anemia

A

retic low, hgb and hct low-normal

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11
Q

Compatible RBCs for Group O blood type

A

O

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12
Q

Compatible RBCs for Group A blood type

A

O and A

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13
Q

Compatible RBCs for Group B blood type

A

O and B

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14
Q

Compatible RBCs for Group AB blood type

A

O, A, B, and AB

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15
Q

Compatible plasma for Group O blood type

A

O, A, B, and AB

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16
Q

Compatible plasma for Group A blood type

17
Q

Compatible plasma for group B blood type

18
Q

Compatible plasma for group AB blood type

19
Q

Abs in group A blood

20
Q

Abs in group B blood

21
Q

Abs in group AB blood

22
Q

Abs in group O blood

A

anti-A and anti-B

23
Q

Rh+ abs

24
Q

Rh- abs

A

MAY develop Anti-D abs

25
Universal RBC donor
O-
26
Universal plasma donor
AB
27
Sickle cell anemia
autosomal recessive condition characterized by predominant variant Hgb, glu->val mutation
28
When does HbS polymerize
when deoxygenated
29
Clinical consequences of sickle cell disease
stroke, acute chest syndrome, hematuria and polyuria, avascular necrosis, autosplenectomy
30
Acute chest syndrome
potentially fatal, initiates by vaso-occlusion caused by marrow emboli from necrosing bone
31
Drug that keeps HbS low
hydroxyurea, decreases HbS and increases HbF
32
Aplastic anemia
pancytopenia associated with bone marrow hypocellularity
33
Etiologies of aplastic anemia
acquired, iatrogenic, physical or chemical injury, genetic disease
34
Drugs that can cause aplastic anemia
chemo, chloramphenicol, chloroquines, NSAIDS, anticonvulsants, heavy metals, sulfonamides