Intro to Pharm Definitions Flashcards

1
Q

Drug

A

substance that brings about a biological change in function through its chemical actions

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2
Q

FDA role

A

ensure drugs are safe and effective

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3
Q

Pro-drug

A

drug that must be converted to it’s active form once inside the body

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4
Q

Pharmacotherapeutics

A

field of study of appropriate use of medications to treat or prevent disease and manage symptoms

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5
Q

Pharmacogenomics

A

field of study of genetic impact on drug metabolism or processes that can affect individual responses to drugs

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6
Q

Pharmacoeconomics

A

field of study utilizing scientific and economic methods to evaluate and compare value between therapies

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7
Q

Pharmacoepidemiology

A

field of study that applies epidemiological principles and methods to study uses and effects of meds on large populations

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8
Q

beta blocker nomenclature

A

-lol, ex: propranolol, atenolol, metoprolol

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9
Q

alpha blocker nomenclature

A

-sin, ex: doxazosin, prazosin, terazosin

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10
Q

ACE Inhibitor nomenclature

A

-pril, ex: benazepril, lisinopril, captopril

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11
Q

Calcium channel blocker nomenclature

A

-pine, ex: amlodipine, felodipine, nifedipine

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12
Q

Diuretic nomenclature

A

-ide, ex: hydrochlorothiazide, furosemide

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13
Q

H2 Receptor antagonist nomenclature

A

-ine, ex: ranitidine, nizatidine, cimetidine

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14
Q

Proton pump inhibitor nomenclature

A

-zole, ex: omeprazole, esomeprazole

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15
Q

Duration of action definition

A

time period between onset of drug effect and end of effect

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16
Q

Therapeutic window definition

A

ratio between minimum effective concentration and minimum toxic concentration

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17
Q

Four classifications of chemical interactions

A

additive, synergistic, potentiation, antagonism

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18
Q

Definition of functional antagonism

A

two agonists interact with different receptors to produce an opposite effect

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19
Q

Definition of chemical antagonism

A

drug counters the effect of another resulting in decreased effect

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20
Q

Definition of dispositional antagonism

A

metabolism of a chemical is altered and concentration and/or duration of chemical are diminished

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21
Q

Definition of receptor antagonism

A

receptor configuration/specificity

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22
Q

Therapeutic equivalence definition

A

must be pharmaceutically equivalent and it is expected to have the same clinical effect and safety profile

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23
Q

Bioequivalence definition

A

similar rate and extent of absorption, 80-125% of reference product

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24
Q

Pharmaceutical alternatives definition

A

same drug but different salts/complexes, or different dosage forms/strengths

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25
Q

“A” Codes for therapeutic equivalence

A

drug products that are considered to be therapeutically equivalent to other pharmaceutically equivalent products

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26
Q

“B” codes for therapeutic equivalence

A

drug products that FDA is considered not to be therapeutically equivalent to other pharmaceutically equivalent products

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27
Q

gm or g

A

grams

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28
Q

mg

A

milligrams

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29
Q

mcg

A

micrograms

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30
Q

mEq

A

milliequivalents

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31
Q

lb

A

pounds

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32
Q

kg

A

kilograms

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33
Q

tsp

A

teaspoon

34
Q

tbsp

A

tablespoon

35
Q

oz

A

ounces

36
Q

ml/cc

A

milliliter/cubic centimeter

37
Q

mL in a tsp

A

5

38
Q

ml in tbsp

A

15

39
Q

ml in an oz

A

30

40
Q

ml in a quart

A

946

41
Q

ml in a pint

A

473

42
Q

L in a gallon

A

3.79

43
Q

Schedule I definition

A

non-research use illegal under federal law, no accepted medical use and a high potential for abuse

44
Q

Schedule II definition

A

no telephone rx’s, no refills, high abuse potential

45
Q

Schedule III definition

A

New Rx written after 6mo or 5 refills

46
Q

Schedule IV definition

A

Rx must be written after 6mo/5 refills, differs from schedule III for illegal possession

47
Q

Schedule V definition

A

non opioid rx dispensed without rx

48
Q

Major reasons for drug therapy failure

A

patient compliance, medication errors

49
Q

Factors that may impact administered dose and drug effects

A

physiologic variables, pathologic factors, genetic factors, interactions with other drugs, development for tolerance

50
Q

three pregnancy risk categories

A

pregnancy (including labor and delivery), lactation, female and male reproductive potential

51
Q

Pregnancy subsection of “Pregnancy Risk Categories” includes information about…

A

dosing and potential risks to the fetus, registry of info that collects data on how pregnant women are affected when they use a product

52
Q

Lactation subsection of “Pregnancy Risk Categories” includes information about…

A

drugs that should not be used during breastfeeding, known data regarding active metabolites in milk, and clinical effects on the infant

53
Q

Females and males of reproductive potential subsection of “Pregnancy Risk Categories” includes information about…

A

pregnancy testing or birth control before, during, or after drug therapy, and a medication’s effect on fertility and pregnancy loss

54
Q

q.d.

A

every day

55
Q

b.i.d.

A

twice daily

56
Q

t.i.d.

A

three times daily

57
Q

q.i.d.

A

four times daily

58
Q

q.o.d.

A

every other day

59
Q

q.”x”h.

A

every x hours

60
Q

q.a.m.

A

every morning

61
Q

q.p.m.

A

every night

62
Q

q.h.s.

A

every night at bedtime

63
Q

p.r.n.

A

as needed

64
Q

a.c.

A

before meals

65
Q

p.c.

A

after meals

66
Q

o.d.

A

right eye

67
Q

o.s.

A

left eye

68
Q

o.u.

A

both eyes

69
Q

a.d.

A

right ear

70
Q

a.s.

A

left ear

71
Q

a.u.

A

both ears

72
Q

drops

A

gtt

73
Q

p.o.

A

by mouth

74
Q

s.l.

A

sublingually

75
Q

i.v.

A

intravenously

76
Q

i.m.

A

intramuscularly

77
Q

s.q.

A

subcutaneously

78
Q

p.r.

A

per rectum

79
Q

NGT

A

naso-gastric tube

80
Q

OGT

A

oro-gastric tube

81
Q

dosage formula calculation

A

one dose = (doctors order/supply on hand) x quantity