Skin Cancer Flashcards

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1
Q

Risks of Basal Cell Carcinoma or Squamous Cancer (6)

A
HPV
Radiation
Photochemo
UV
Familial Cancer
Immunosuppression
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2
Q

Basal Cell Carcinoma features?

A

Slow Growth
Local Invasion
Pearly Rolled

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3
Q

Telangiectasia is associated with what type of skin cancer?

A

Basal Cell Carcinoma

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4
Q

Arborising Vessels on Dermatoscope would suggest what type of Skin Cancer?

A

Basal Cell Carcinoma

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5
Q

How to treat BCC Skin Cancer?

A

Excision
Imiquimod
Moh’s Surgery
Visomodegib

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6
Q

How to treat someone not suitable for surgery or radiotherapy or has metastatic bcc skin cancer?

A

Visomodegib

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7
Q

Visomodegib action?

A

Selectively inhibits hedgehog pathway (molecular driver in BCC)

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8
Q

Squamous Cell Carcinoma comes from?

A

Keratinocytes

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9
Q

Squamous cell carcinoma particularly happen where?

A

Sun exposed sites

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10
Q

What type of skin cancer can metastasise?

A

Squamous Call Carcinoma

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11
Q

How to treat SCC cancer?

A

Exicision and Radiotherapy

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12
Q

Keratoacanthoma features (2)

A

Squamous Cell Cancer

Hair Follicles

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13
Q

Melanoma key features to look for?

A

Size, Shape, Colour

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14
Q

Melanoma minor features to look for?

A

> 5mm, Inflammed, Ooze or Bleed, Mild Itch

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15
Q

Treatment of Melanoma?

A

Exicison

Sentineal lymph node biopsy

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16
Q

How to treat Metastatic Melanoma? (4)

A

Ipiqimab
Pembrodlizimab
Nivolumab
Trametinib

17
Q

Ipilimab action?

A

Inhibits CTLA-4

18
Q

Tramotinib should be used with?

A

Veminifenib and Dabrafenib

19
Q

Cutaneous Lymphoma features?

A

T Cell Lymphoma
Mycosis Fungiodes (Most Common)
Sezary Syndrome

20
Q

What stages of Cutaneous Lymphoma? (4)

A

Patch
Plaque
Tumour
Mets

21
Q

Diagnosis of Cutaneous Lymphoma?

A

Sezary Cells in Bloods

CT

22
Q

What is Sezary Syndrome?

A

Red Man Syndrome

23
Q

Treatment of cutaneous lymphoma? (8)

A
Topical Steroids
PUVA or UVB
Interferon
Bexaotene
Low Dose Methotrexate
Total Skin Electron Beam
Extracorporeal Photophoresis 
Bone Marrow Transplant
24
Q

What is collected in Extracorporeal Photophoresis?

A

Leucocytes

25
Q

Why Cutaneous Mets due to cancer where? (4)

A

Melanoma
Breast
Colon
Lung