Skin Cancer Flashcards
Risks of Basal Cell Carcinoma or Squamous Cancer (6)
HPV Radiation Photochemo UV Familial Cancer Immunosuppression
Basal Cell Carcinoma features?
Slow Growth
Local Invasion
Pearly Rolled
Telangiectasia is associated with what type of skin cancer?
Basal Cell Carcinoma
Arborising Vessels on Dermatoscope would suggest what type of Skin Cancer?
Basal Cell Carcinoma
How to treat BCC Skin Cancer?
Excision
Imiquimod
Moh’s Surgery
Visomodegib
How to treat someone not suitable for surgery or radiotherapy or has metastatic bcc skin cancer?
Visomodegib
Visomodegib action?
Selectively inhibits hedgehog pathway (molecular driver in BCC)
Squamous Cell Carcinoma comes from?
Keratinocytes
Squamous cell carcinoma particularly happen where?
Sun exposed sites
What type of skin cancer can metastasise?
Squamous Call Carcinoma
How to treat SCC cancer?
Exicision and Radiotherapy
Keratoacanthoma features (2)
Squamous Cell Cancer
Hair Follicles
Melanoma key features to look for?
Size, Shape, Colour
Melanoma minor features to look for?
> 5mm, Inflammed, Ooze or Bleed, Mild Itch
Treatment of Melanoma?
Exicison
Sentineal lymph node biopsy
How to treat Metastatic Melanoma? (4)
Ipiqimab
Pembrodlizimab
Nivolumab
Trametinib
Ipilimab action?
Inhibits CTLA-4
Tramotinib should be used with?
Veminifenib and Dabrafenib
Cutaneous Lymphoma features?
T Cell Lymphoma
Mycosis Fungiodes (Most Common)
Sezary Syndrome
What stages of Cutaneous Lymphoma? (4)
Patch
Plaque
Tumour
Mets
Diagnosis of Cutaneous Lymphoma?
Sezary Cells in Bloods
CT
What is Sezary Syndrome?
Red Man Syndrome
Treatment of cutaneous lymphoma? (8)
Topical Steroids PUVA or UVB Interferon Bexaotene Low Dose Methotrexate Total Skin Electron Beam Extracorporeal Photophoresis Bone Marrow Transplant
What is collected in Extracorporeal Photophoresis?
Leucocytes
