Pharmacology Flashcards
What is Pharmcokinetics?
Effect of body on drug
What is pharmcodynamics?
Effect of drug on body
What do topical steroids suppress? (2)
Fibroblasts
Endothelial and Leukocyte Function
Side Effects of Topical Steroids? (5)
Hirtuism Telenagiectasia Dermatitis Glaucoma Cataract
Action of Retinoids?
Vit A Analogue
Vit A Analogues do what?
Normalise Keratinocytes
What Retinoid can be used in Cutaneous T Cell Lymphoma?
Bexarotene
Retinoids side effects (5)
Teratogenic Chelitis Dry Skin Increased Transaminases Increased Triglycerides
Name 4 Immunosuppressive Dermatology Drugs?
Azathioprine
Ciclosporin
Methotrexate
Mycophenolate Mofetil
Cyclosporin needs what regular blood test?
Renal Bloods
Methotrexate needs what regular blood test?
Liver Bloods
Biologic drugs risk the reactivation of what?
Tuberculosis
Inhibiting TNF risks what?
Demyelination
What vaccine should be avoided when using biologics?
Live Vaccines
What mutation is present in melanoma?
BRAF 600