Pharmacology Flashcards

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1
Q

What is Pharmcokinetics?

A

Effect of body on drug

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2
Q

What is pharmcodynamics?

A

Effect of drug on body

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3
Q

What do topical steroids suppress? (2)

A

Fibroblasts

Endothelial and Leukocyte Function

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4
Q

Side Effects of Topical Steroids? (5)

A
Hirtuism 
Telenagiectasia
Dermatitis
Glaucoma
Cataract
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5
Q

Action of Retinoids?

A

Vit A Analogue

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6
Q

Vit A Analogues do what?

A

Normalise Keratinocytes

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7
Q

What Retinoid can be used in Cutaneous T Cell Lymphoma?

A

Bexarotene

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8
Q

Retinoids side effects (5)

A
Teratogenic
Chelitis
Dry Skin
Increased Transaminases
Increased Triglycerides
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9
Q

Name 4 Immunosuppressive Dermatology Drugs?

A

Azathioprine
Ciclosporin
Methotrexate
Mycophenolate Mofetil

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10
Q

Cyclosporin needs what regular blood test?

A

Renal Bloods

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11
Q

Methotrexate needs what regular blood test?

A

Liver Bloods

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12
Q

Biologic drugs risk the reactivation of what?

A

Tuberculosis

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13
Q

Inhibiting TNF risks what?

A

Demyelination

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14
Q

What vaccine should be avoided when using biologics?

A

Live Vaccines

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15
Q

What mutation is present in melanoma?

A

BRAF 600

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