Eczema

Question 1

Eczema is also known as?

Answer 1

Atopic Dermatitis

Question 2

Eczema is common where?

Answer 2

Flexors

Question 3

Pathogenesis of Eczema?

Answer 3

Filaggrin Gene

Question 4

Pathology of Eczema? (2)

Answer 4

Spongiosis (intracellular oedema) in epidermis

Acanthosis

Question 5

Lichnification Plaques are present in what type of eczema?

Answer 5

Chronic Eczema

Question 6

Allergy Contact Eczema is what type of hypersensitivity reaction?

Answer 6

Type 4

Question 7

How long does a Type 4 Reaction take?

Answer 7

48 hrs to 72 hours

Question 8

Physiology of Allergy Contact Eczema? (5)

Answer 8

Hapten 
Clonal T Cell expansion
Mast Cell Degranulation
Neutrophils
Vasodilation

Question 9

Seborrhoeic Dermatitis particularly affects?

Answer 9

Infants

Question 10

Seborrhoeic Dermatitis particularly affects where?

Answer 10

Scalp and Proximal Flexures

Question 11

What yeast affects Seborrhoeic Dermatitis in adults?

Answer 11

Malassezia Yeast

Question 12

How to treat Seborrhoeic Dermatitis in adults?

Answer 12

Topical Anti Yeast - Ketoconazole

Question 13

Pompholyx/Vesicular Dermatitis particularly affects where?

Answer 13

Palms and Soles

Question 14

Eczema Herpeticum is what?

Answer 14

Disseminated Virus Herpes Simplex 1 and 2

Question 15

How to Treat Eczema?

Answer 15

Low Hydrocortisone
Betomethasone
Topical Pimecrotimus and Tacrolimus
Immunosuppressive: Azathioprine, Ciclosporin, Mycophenolate Mofetil, Methotrexate
Biologics: Duplimab (IL 4 and iL3 Inhibit)

Question 16

What type of biologics to treat Eczema?

Answer 16

Biologics: Duplimab (IL 4 and iL3 Inhibit)