Skin and Systemic Diseases Flashcards
Liver Disease presentation on skin
Jaundice, Palamr erythema, purpura, spider angiomas, itch (Pruritus)
Kidney Disease presentation on skin
Itch, Calcinosis, perforating disorders, Half and Half nails
Calciphylaxin
Seen in dialysis patients. When calcium accumulates in fat and skin tissues causing blood clot, ulcers and maybe even death.
Dermatitis herpetiformis
Seen in Coeliacs
Pyoderma gangrenosum
Seen in those with haematological malignancy, IBD and rheumatoid
Zinc deficiency
Acrodermatitis Enteropathica
Nicotinic acid deficiency
Pellagra: vitamin B3 deficiency, marked by dementia, diarrhea, and dermatitis
Xanthalsmas
Lipid deposition
Acanthosis nigracans
Necrobiosis lipodica
Thrush
Seen in diabetics
Erythema nodosum
fat inflammation, bruise-like common in young women and seen in lower legs. Suggest pregnancy, sarcoidosis, IBD or infection
Connective tissue diseases
Lupus
Systemic Sclerosis
Dermatomyositis
Rheumatoid arthritis
Lupus Erthematosus
Autoantibodies drive inflammation in the skin
Different types of Lupus
Discoid (DLE)
Sub-acute cutaneous (SACLE)
Systemic (SLE)
Morphea
Painless, discolored patches on your skin. Seen as ivory white sclerotc plaques with inflamed edges.
Paraneoplastic syndromes
Acanthosis nigracans
Sweets syndrome
Erythema gyratum repens