Acne & Roseaca Flashcards
Pathogenesis of Acne
Androgens cause increase sebum production, changes in skin and inflammation
What bacteria colonises hair follicles
Propionibacterium acnes
Commonly affected by acne
Teenagers, adolescents
Presentation of acne
Seborrhoea, comedones, papules, pustules nodules and cysts, scarring
Seborrhoea
Excessive discharge of sebum from hair follicles
Leeds Acne Grading System
Pictorial grades of facial acne, back and chest
Acne treatment: Benzoyl Peroxide
in gels, cream or face wash, antibacterial, comedolytic, bleaching
Acne treatment: Retinoids e.g Adapalene, Tretinoin
Vitamin A based drugs, increases production of collagen reducing fine lines and wrinkles , photosensitive
Acne treatment: Topical antibiotics
Erythromycin + Zinc
Clindamycin + Benzoyl Peroxide
Acne Treatments: System
Anti-androgens contraceptives e.g. Dianette, Yasmin
Acne treatment: systemic antibiotics
Erythromycin, Lymecycline, Trimethoprim
Isotretinoin
- For severe acne, 4-6 month course
- 90% risk of birth defects, contraception mandatory, monthly pregnancy test required
- Elevated liver enzymes
- Elevated lipids
- Drying
- Depression, suicide
Other acne treatments
Intra-lesional steroid injections
Oral steroid
Hyfrecation (low grade electro-surgical diathermy) of comedones
Laser
Rosacea
Poorly understood long-term skin condition that affects the face. Often due to sun damage
Commonly affected by Rosacea
Middle-aged
