Skin and Soft Tissue Infections Flashcards

1
Q

What things should be considered when treating a skin or soft tissue infection?

A

Site, Organism, Host, Environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is impetigo?

A

Superficial skin infection, multiple vesicular lesions on an erythematous base, golden crust is highly suggestive of diagnosis, most commonly due to staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Who does impetigo most commonly infect?

A

Common in children 2-5 years of age

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where does impetigo usually occur?

A

Exposed parts of the body such as the face, extremities and scalp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the predisposing factors for impetigo?

A

Skin abrasions, burns, minor trauma, poor hygiene, insect bites, chicken pox,eczema, atopic dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the treatment for impetigo?

A

Topical antibiotics (small areas) or oral antibiotics (flucloxacillin) + topical treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is erysipelas?

A

Infection of the upper dermis, painful red area with associated fever. Regional lymphadenopathy and lymphangitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What organism causes erysipelas?

A

Strep pyogenes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is cellulitis?

A

Diffuse skin infection involving deep dermis and subcutaneous fat.

Most likely to be caused by strep pyogenes and staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How are erysipelas and cellulitis treated?

A

Anti-staph and anti-strep antibiotics.

If disease extensive = IV antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is folliculitis?

A

A circumscribed pustular infection of hair follicle up to 5mm in diameter. Present as a small red papule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Where on body is folliculitis common?

A

Head, back, buttocks and extremities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What organism causes folliculitis?

A

Staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is furunculosis?

A

Commonly referred as boils. Single hair follicule associated inflammatory nodule extending into dermis and subcutaneous tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What areas of body are most likely to be affected by furunculosis?

A

Face, axilla, neck and buttocks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is most likely to cause furunculosis?

A

Staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the risk factors for furunculosis?

A

Obesity, DM, Atopic dermatitis, chronic kidney disease, corticosteroid use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the presence of multiple furuncles known as?

A

Neck, posterior trunk or thigh

19
Q

How should hair associated infections be treated?

A
Folliculitis = no treatment
Furunculosis = no treatment or topical antibiotics. Oral antibiotics may be mecessary
Carbuncles = often require admission to hospital, surgery and antibiotics
20
Q

What is necrotising fasciitis ?

A

Infectious disease emergency

Erythema, extensive oedema and severe unremitting pain. Haemorrhagic bullae, skin necrosis and crepitus may develop

21
Q

What systemic features are associated with necrotising fasciitis?

A

Fever, hypotension, tachycardia, delirium, multiorgan failure

22
Q

What is the treatment for necrotising fasciitis?

A

Flucloxacillin, gentamicin, clindamycin

23
Q

What is pyomyositis?

A

Purulent infection deep within striated muscle often manifesting as an abscess

24
Q

What are common sites of pyomyositis?

A

Thigh, calf, arms, gluteal region, chest wall, psoas muscle

25
How does pyomyositis present?
Fever, pain, woody induration of affected muscle and if left untreated, can lead to septic shock and death
26
What are the predisposing factors for pyomyositis?
Diabetes mellitus, HIV/immunocompromised, IV drug use, rheumatological diseases, malignancy, liver cirrhosis
27
What is the organism that causes pyomyositis?
Staph aureus
28
What is the treatment for pyomyositis?
Drainage and antibiotics
29
What is septic bursitis?
Infection of bursae, usually from adjacent skin infection
30
What factors can predispose you to septic bursitis?
Rhematoid arthritis, alcoholism, DM, IV drug abuse, immunosuppression, renal insufficiency
31
What are the symptoms of septic bursitis?
Peribursal cellulitis, swelling, warmth, fever and pain on movement
32
How is septic bursitis diagnosed?
Aspiration of the fluid
33
What is the cause of septic bursitis?
Staph aureus
34
What is infectious tenosynovitis?
Infection of the synovial sheaths that surround tendons
35
What causes infectious tenosynovitis?
Penetrating trauma
36
What are the symptoms of infectious tenosynovitis?
Erythematous fusiform swelling of finger held in a semiflexed position. Tenderness and pain are classical
37
What organisms cause TSS?
Staph aureus and strep pyogenes
38
What is the mechanism behind TSS?
Superantigens attatch to T Cell receptors, activating T cells causing cytokine release which leads to endothelial leakage, haemodynamic shock, multi organ failure
39
What is the diagnostic criteria for staphylococcal TSS?
Fever, hypotension, diffuse macular rash, 3 of either LIVER, BLOOD, RENAL, GI, CNS, MUSCULAR systems involved, isolation of staph aureus from mucosal or normally sterile sites, production of TSST1 by isolate, development of antibody to toxin during convalescence
40
Which version of TSS has the highest mortality rate?
Streptococcal TSS
41
What is the treatment of Strep TSS?
Surgical debridement of infected tissue
42
What is treatment of TSS?
Removal of offending agent, IV fluids, Inotropes, Antibiotics, IV immunoglobulin
43
What is Staphylococcal Scalded Skin Syndrome?
Infection due to a particular strain of Staph Aureus producing exfoliative toxin A/B. Bullae and skin exfoliation. Occurs in children. Treat with iv fluids and antimicrobials
44
What are the causes of surgical site infections?
``` Staph Aureus Coagulase negative Staphylococci Enterococcus E. Coli Pseudomonas Aeruginosa Enterobacter ```