Skin and Fascia 1: Epidermis Flashcards
What are the functions of the skin?
Function 1: Protection
Function 2: Sensation
Function 3: Excretion
Function 4: Thermoregulation
Function 5: Metabolic
Describe the protective functions of the skin
Function 1
Cushions and insulates deeper organs
Ultraviolet light & microorganisms
Abrasion, trauma, chemical, mechanical insults
Prevents water loss
What sensations can be detected by the skin?
Function 2
Contains sensory receptors for Pain, Pressure, Touch & Temperature
What are the excretions of the skin?
Function 3
Sweat
How is skin involved in thermoregulation?
Function 4
Vasodilation & Vasoconstriction
Describe the metabolic functions of the skin
Function 5
Vitamin D synthesis
What are the layers of the skin?
Epidermis: Superficial stratified squamous epithelium layer
Dermis: Deep connective tissue layer
What lies deep to the dermis layer of skin?
Hypodermis/subcutaneous layer
It is a layer of areolar and adipose connective tissue
Not considered part of the skin
What are the layers of the epidermis?
Deep to superficial (Britney Spears Gives Lovely Concerts):
1. Stratum basale/stratum germinativum
2. Stratum spinosum
3. Stratum granulosum
4. Stratum lucidum
5. Stratum corneum
Features of stratum basale
Continuous cell division occurs to produce all the other layers
Features of stratum spinosum
8-10 layers of keratinocytes
Features of stratum granulosum
Includes keratohyalin and lamellar granules
Features of stratum lucidum
Present only in thick skin, e.g. skin of the fingertips, palms, and soles
Features of stratum corneum
Composed of many sublayers of flat, dead keratinocytes called corneocytes or squames
They are continuously shed and replaced by cells from deeper strata
Constant friction can stimulate formation of a callus.
What are the 4 major types of epidermal cells?
Keratinocytes: Produce keratin (a tough fibrous protein) that provides protection. Forms 90% of the epidermal layer
Melanocytes: Produce melanin pigment which protects against damage by UV radiation
Langerhans Cells: Cells arising from red bone marrow which trigger immune reactions
Merkel Cells: Function in the sensation of touch along with adjacent tactile discs