Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Anatomy > Skin > Flashcards

Skin Flashcards

1
Q

Epidermis structure x3

A
  • Epithelial
  • Avascular
  • Synthesises keratin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Dermis structure x3

A
  • Strong CT
  • Collagen & elastic fibres
  • Quite vascular
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hypodermis structure x3

A
  • Looser CT
  • Superficial fascia
  • Blood vessels, lymph
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where are glands in the skin?

A

Buried in dermis/hypodermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Epidermis layers x5 (base –> surface)

A
  • S. Basale
  • S. Spinosum
  • S. Granulosum
  • S. Lucidum
  • S. Corneum
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

S. Corneum

  • layer (from base)
  • structure
A
  • 5th

- Water-proof cell ghosts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

S. Lucidum

  • layer (from base)
  • processes
A
  • 4th

- Specialised death programme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

S. Granulosum

  • layer (from base)
  • processes
A
  • 3rd

- cells accumulate keratohyaline granules & start to die

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

S. Spinosum

  • layer (from base)
  • structure
A
  • 2nd

- Spiky= diff. immediate filaments join through desmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

S. Basale

  • layer (from base)
  • processes
A
  • 1st

- Stem cells divide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Stratum Basale

  • what cells
  • function
A
  • Stem cells

- Anchoring layer –> hemidesmosomes link w CT underneath

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does S. Basal connect to the BM

A

Hemodesmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How does the dermis anchor to the basal lamina (= S. Basal BM)

A

Collagen VII

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happens if collagen in the S. Basal is mutated

A

Blistering

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Stratum Spinosum

  • structure
  • expression of…
  • at ‘end’ near S. Granulosum…
A
  • Spikey –> due to desmosomes
  • K1 & K10 (keratin)
  • Filaggrin –> organises filaments as the cells die
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Filaggrin

  • what
  • where
  • when
  • function x2
A
  • Main component of keratohyaline granules
  • Stratum Spinosum
  • As cells start their death programme
  • Organises filaments as the cells die
  • Natural moisturiser
17
Q

Melanocytes

  • where
  • what
  • function
A
  • Basal layer
  • Release melanin
  • Absorbs UV, preventing DNA damage
18
Q

Keratinocytes & melanin

A

Engulf melanin molecules –> form melanosomes

19
Q

Langherhans cells (monocytes)

  • where
  • structure x2
  • function
A
  • Epidermis
  • Dendritic (big processes)
  • Specialised lysosomes –> can degrade viruses
  • Migrate to lymph nodes & present antigens
20
Q

Dermis

- sections x3

A
  • Demo-epidermal junction
  • Papillary dermis
  • Reticular dermis
21
Q

What is the dermo-epidermal junction

A
  • Where collagen VII connects in the dermis (to the epidermis)
22
Q

What is the papillary dermis?

A
  • Contains lymphatics, sensory nerve endings

- Less dense than reticular dermis = below

23
Q

What is the reticular dermis?

A
  • Below the papillary dermis

- Coarse collagen & elastic fibres

24
Q

Hypodermis

  • structure
  • components x4
A
  • Loose connective & adipose tissue
  • Sweat glands
  • Hair follicles
  • Vascular
  • Ligaments –> determine skin motility
25
Q

Sweat glands in skin x2

A
  • Merocrine/eccrine

- Apocrine

26
Q

Merocrine/eccrine glands

  • structure
  • Function
A
  • Tubular gland = straightens into tubular duct

- Thermoregulation –> sweat

27
Q

Apocrine glands

  • structure
  • secretion
A
  • In axillae, around hair follicles

- Alkaline –> odorous –> pheromones

28
Q

Hairs

  • structure
  • location
  • gland
  • movement
A
  • Modified epithelium (as rod of keratin)
  • Hair follicle in hypodermis
  • Sebaceous –> = oil secretion gland
  • Arrector pilli miscela –> driven by autonomic nervous system
29
Q

Pilosebaceous unit

- components x4

A
  • Hair follicle
  • Sebaceous glands
  • Hair shaft
  • Arrector pili muscle
30
Q

What are mammary glands?

A

Modified apocrine glands

31
Q

Functions of skin x3

A
  • Barrier
  • Strength
  • Secretion
32
Q

Multifunctional skin

- what it does x3

A
  • Protection (UV, organisms)
  • Homeostasis (metabolic, temp. reg)
  • Sensory info
33
Q

Mutations resulting in less filaggrin cause….

A

Larger risk of eczema (50% of eczema cases = this mutation)

Anatomy (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions