Skeletal system Flashcards
what are the 2 types of bone? describe
cortical/compact bone - weight bearing; has osteons
spongy bone - has holes/porous; NOT weight bearing; deep to compact bone
List some functions of Bone
support and protection
movement
hemopoiesis
storage - calcium and phosphate and fat
How are bones classified? List the 4 classes of bone
classified by shape
- long bones - longer than width ex. limbs
- short bones - length almost = width ex. carpal bones of wrist/tarsal bones of foot
- flat bones - flat thin surfaces, may be slightly curved ex. ribs, sternum, scapulae, some of the cranial bones
- irregular bones ex. vertebrae
what are the two sesamoid bones that are counted as proper bones?
patella and pisiform
name and describe the regions/anatomy of long bones
epiphysis - proximal/distal ends; attached to articular cartilage
diaphysis - cylindrical shaft in middle
medullary cavity - hollow space in middle of diaphysis; bone marrow storage
what is the epiphyseal plate?
thin layer of hyaline cartilage for continued lengthwise bone growth
becomes the epiphyseal LINE in adults when growth ends
What is the periosteum? describe its anatomy
outer surface of bone
2 layers
- fibrous layer outer
-inner cellular layer - osteoprogenitor cells (stem cells), osteoblasts, and osteoclasts
attached to bone by perforating fibers (collagen)
what is the endosteum? describe anatomy and list the cells it houses
covers internal surfaces of LONG bones w/in medullary cavity
contains osteoprogenitor cells, osteoblasts, and osteoclasts
what is the nutrient foramen(foramina)? what is it’s significance?
small opening in bone for veins, arteries, and nerves
what is the spongy bone in the cranial flat bones called?
Diploë
List the 4 bone cells. describe them
osteoprogenitor cells - stem cells tht become osteoblasts
osteoblasts - make and secrete osteoid (organic part of matrix)
osteocytes - mature bone cells derived from osteoblasts ; maintain bone matrix
osteoclasts - break down bone to increase blood Ca++ levels
what are the 2 parts of bone matrix? how does each contribute to the characteristics of bone?
organic component = osteoid => collagen, proteoglycans, glycoproteins; made by osteoblasts; gives bone flexibility
inorganic = minerals => calcium phosphate makes hydroxyapatite crystals around collagen, which gives bones its rigidity
name the process in which new bone is formed
ossification
what are the 2 types of ossification? how do they differ
intramembranous - only in flat bones of cranium, some facial bones, mandible and clavicle
endochondral - starts with hyaline cartilage fetal model; makes most bones of skeleton; upper/lower limbs; pelvis and vertebrae
where does primary/secondary ossification centers form during endochondral ossification?
primary - diaphysis
secondary - epiphysis
during endochondral ossification, almost all cartilage is replaced by bone expect for…?
articular cartilage where joints articulate and epiphyseal plates
what is required for healthy bone formation>
vitamin C - collagen formation
vitamin D - calcium absorption
calcium and phosphate = calcification
at what part of the bone does continuous bone remodeling occur?
periosteal and endosteal surfaces
what can effect bone remodeling
mechanical stress or lack of mech. stress - weight bearing movement/exercise
hormones - GH, Thyroid hormones sex hormones calcium regulators
what 2 primary hormones regulate blood Ca++
parathyroid hormone, calcitriol
elevate blood Ca++ to normal range
regulated via negative feedback
what is blood Ca++ needed for>
muscle contraction, nervous system, stimulation of heart, blood clotting