Sjögren's Syndrome

Question 1

Name all causes of dry mouth?

Answer 1

1) radiotherapy In the region of salivary gland
2) diabetes
3) dehydration
4) mumps
5) HIV infection
6) anxiety stress
7) diuretics
7) sarcoidosis
8) sjögren’s
9) Amyloidosis
10) drugs : - antimuscarinics
- antihistamine
- antidepressant

Question 2

What is the diff fence between primary and secondary Sjögren’s syndrome ?

Answer 2

Primary= only dry eyes and dry mouth 
Secondary =dry mouth and dry eyes+ connective tissue disease ( such as ): 
- rheumatoid arthritis 
-systemic lupus 
-erythematosus

Question 3

What type of biopsy is carried out to diagnose sjögrens and why?

Answer 3

Labial salivary gland biopsy

Because the minor glands are usually involved at a microscopic level even though they may not be enlarged

Question 4

What microscopic feature would the biopsy show if pat had Sjögren’s syndrome?

Answer 4

Focal collection of lymphoid cells are seen adjacent to