Sinusitus Flashcards

1
Q

Frontal Sinuses

A

Eyebrow area
- Appear after 5th year and develop into adolescence

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2
Q

Maxillary Sinuses

A

Inside both cheekbones
- Present since birth

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3
Q

Ethmoid Sinuses

A

Between the eyes behind the bridge of the nose
- Present since birth

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4
Q

Sphenoid Sinuses

A

Behind the eyes and above the bridge of the nose
- Appear by 3rd year and develop until 12th year

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5
Q

Sinusitis
- Most Common Predisposing Factor

A

Viral Upper Respiratory Infection
- Ostia are obstructed from inflammation caused by viral infection / allergen
- Cilia are immobile due to viruses or smoke
–> Bacteria and fluid become trapped and thus, can proliferate

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6
Q

Sinusitis
- Predisposing Factors

A

Medical Conditions
- Respiratory infections
- Allergic rhinitis
- Cystic fibrosis

Irritants
- Pollution
- Tobacco smoke

Anatomic
- Deviated nasal septum
- Immotile cilia

Medications
- Overuse of nasal decongestants
- Cocaine abuse

Trauma
- Diving, Dental procedure

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7
Q

Sinusitis
- Symptoms

A
  • Fever
  • Nasal congestion
  • Maxillary toothache
  • Facial pain
  • Cough (More so in children)
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8
Q

Acute Sinusitis
- Diagnosis: What not to use

A

Colour of sputum
- Is only related to neutrophil count, should not be used to diagnose sinusitis

X-Ray

CT Scans

Culture of nasal discharge

Illumination of sinuses

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9
Q

Acute Sinusitis
- Diagnosis: Gold Standard

A

Puncture aspirate of sinus fluid
- Invasive procedure, only really done in treatment failure

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10
Q

Acute Sinusitis
- Diagnosis

A

Requires at least 2 of the following
- P: Facial Pain, Pressure/Fullness
- O: Nasal Obstruction
- D: Nasal Purulence / Discoloured postnasal Discharge
- S: Hyposmia / Anosmia (Smell)

1 one of the must be Nasal Obstruction or Postnasal Discharge

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11
Q

What bacteria pathogens cause Sinusitis

A

50%:
- S. Pneumoniae
- H. Influenzae

20%:
M. Catarrhalis

10%:
Anaerobes

20% will have respiratory viruses alone or with bacterial pathogens
- Rhinovirus
- Influenza / Parainfluenza

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12
Q

What bacteria pathogens rarely cause Sinusitis

A

S. Aureus
S. Pyogenes
Aerobic Gram-Negative Organisms

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13
Q

Bacterial Sinusitis vs Viral Sinusitis

A

Bacterial Sinusitis
1. Persistent symptoms
2. Severe symptoms
3. Double Sickening

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14
Q

What is Persistient Symptoms

A

Symptoms that last longer than 10 days with no sign of getting better

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15
Q

What are Severe Symptoms of Bacterial Sinusitis

A

Fever greater than 39°C and Purulent Nasal Discharge or Facial Pains for longer than 3-4 days

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16
Q

What is Double Sickening

A

A sign of Bacterial Sinusitis

After a Viral Sinusitis Infection that lasted 5-6 days and was initially improving the patient develops new symptoms of:
- New onset of fever
- Increase in nasal discharge
- Headache

17
Q

Sinusitis
- Management Treatment

A

Works for both Viral and Bacterial Sinusitis
- Analgesics (Pain)
- Normal Saline (Nasal Irrigation)
- Steam Inhalation
- Intranasal Decongestant (Short Duration)

Works if there is an allergic component
- Second Generation Antihistamines
- Nasal Corticosteroid
* First Generation Antihistamine not recommended

If patient meets criteria for Bacterial Sinusitis
- Selective Antibacterial Therapy

18
Q

Acute Sinusitis - No Beta-Lactam Allergy
- Treatment

A

Amoxicillin 500 mg - 1g tid
- Use 1g if patient has had recent antibacterial use in last 3 months
- Shorter therapy demonstrates better efficacy

19
Q

Acute Sinusitis - No Beta-Lactam Allergy
- Treatment (Severe/Immunocompromised)

A

If Fever greater than 39°C and Purulent Nasal Discharge or Facial Pain
- Amoxicillin 1g bid + Amox/Clav 875 mg bid

20
Q

Acute Sinusitis - Beta-Lactam Allergy
- Treatment

A

Doxycycline

21
Q

Acute Sinusitis - Beta-Lactam Allergy
- Treatment (Severe/Immunocompromised)

A

Non-Severe Allergy
- Ceftriaxone

Severe Allergy
- Levofloxacin

22
Q

Acute Sinusitis - No Beta-Lactam Allergy
- Treatment (Treatment Failure)

A

If patient was initially on Amox 500 mg tid
- Amox 1g po bid + Amox/Clav 875 mg po bid

If patient was initially on Amox 1g tid
- Amox/Clav 875 mg po bid

23
Q

Acute Sinusitis - Beta-Lactam Allergy
- Treatment (Treatment Failure)

A

Levofloxacin

24
Q

Sinusitis
-Re-currence within 3 months even after using treatment failure options

A
  • Consider allergy testing
  • Topical intranasal corticosteroid can provide benefit, should be used before ostea closure
  • Refer to ENT if 4 or more episodes per year
25
Acute Sinusitis - No Beta-Lactam Allergy - Treatment (Pediatrics)
Is patient <2 years, daycare, or recent antibacterials within 3 months - Yes: Amoxicillin 90 mg/kg/day bid or tid - No: Amoxicillin 40 mg/kg/day tid
26
Acute Sinusitis - No Beta-Lactam Allergy - Treatment (Pediatrics + Severe/Immunocompromised)
Amoxicillin 45 mg/kg/day bid or tid + Amox/Clav 7:1 45 mg/kg/day bid or tid
27
Acute Sinusitis - Penicillin Allergy - Treatment (Pediatric + Non-Severe)
Non-Severe: - Clindamycin + Cefixime OR - Cefuroxime
28
Acute Sinusitis - Penicillin Allergy - Treatment (Pediatric + Severe/Immunocompromised)
Non-Severe Allergy: - Ceftriaxone Severe Allergy and Local Resistance < 20%: - Doxycycline (Must be older than 8 yrs) - TMP/SMX Severe Allergy and Local Resistance > 20%: - Levofloxacin
29
Acute Sinusitis - No Beta-Lactam Allergy - Treatment (Pediatric + Treatment Failure)
If patient failed high dose: - Amox/Clav 45 mg/kg/day bid or tid If patient failed regular dose: - Amoxicillin 45 mg/kg/day bid or tid + - Amox/Clav 45 mg/kg/day bid or tid
30
Acute Sinusitis - Beta Lactam Allergy - Treatment (Pediatric + Treatment Failure + Non-Severe)
Clindamycin + Cefixime
31
Acute Sinusitis - Beta Lactam Allergy - Treatment (Pediatric + Treatment Failure + Severe/Immunocompromised)
Non-Severe Allergy - Ceftriaxone Severe (Pen or Ceph) Allergy - Levofloxacin
32
General Rule for Serious/Immunocompromised
Use Ceftriaxone