Bacterial Pathogens 3 Flashcards by Kevin Tea

Treponema Pallidum
- Identification

Spiral-Shaped
Systemic Disease causing
- Causes Syphilis

How well did you know this?

Not at all

Perfectly

Stages of Syphylius

Primary
Secondary
Tertiary
Latent
Congenital

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Primary

Incubation Period
- 3 Weeks

Symptoms
- Chancre
- Lymphadenopathy

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Secondary

Incubation Period
- 2-12 weeks

Symptoms
- Rash
- Fever
- Meningitis

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Teritary

Cardiovascular
Neurosyphilis
Gummatous

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Cardiovascular

Tertiary

Incubation Period
- 10-30 years

Symptoms:
- Aortic aneurysms
- Aortic regurgitations
- Coronary arterial ostial stenosis

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Neurosyphilis

Tertiary

Incubation Period
- 2-20 years

Symptoms:
- Dementia, headache, vertigo

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Gummatous

Tertiary

Incubation Period:
- 15 years

Symptoms:
- Mass like lesions anywhere

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Latent

Incubation Period
- < 1 year = early
- > 1 year = late

Symptoms:
- Asymptomatic

How well did you know this?

Not at all

Perfectly

Stages of Syphilis
- Congenital

Incubation Period
- N/A

Symptoms:
- Mucocutaneous lesions, anemia, hepatosplenomegaly, neurosyphilis

How well did you know this?

Not at all

Perfectly

Borrelia Burgdorferi
- Identification

Spiral-Shaped
Systemic Disease Causing
- Lyme Disease (Transmitted via tick bites)

How well did you know this?

Not at all

Perfectly

Stages of Lyme Disease
- Early Localized

Time after tick bite:
- Days to 1 month

Symptoms:
- Erythema Migrans
- Non-specific: fever, fatigue,

How well did you know this?

Not at all

Perfectly

Stages of Lyme Disease
- Early Disseminated

TIme after tick bite:
- Weeks to Months

Symptoms:
- Carditis, Neurologic disease, liver disease, kidney disease
-Multiple erythema migrans

How well did you know this?

Not at all

Perfectly

Stages of Lyme disease
- Late Disseminated

Time after tick bite:
- Months to Years

Symptoms:
- Arthritis of joints
- Neurologic disease
- Skin disease

How well did you know this?

Not at all

Perfectly

Leptospira
- Identification

Spiral-Shaped
Systemic Disease Causing
- Spread by rodents

How well did you know this?

Not at all

Perfectly

Leptospira
- Infection

Entry through cuts, ingestion, mucous membranes

Symptoms: (Ranges from Mild –> Death)
- Fever, Nausea
- Meningitis
- Kidney failure, Liver dysfunction

Helicobacter Pylori
- Identification

Curved-Shaped
GI Disease Causing
Causes:
- Peptic Ulcer Disease
- Gastritis

Helicobacter Pylori
- Pathophysiology

Converts H2O + Urea into Ammonia and CO2
Neutralizes acidic gut environment
Attaches to gastric epithelial cells through adhesions
Releases toxins that damage the host

What bacterias have different cell walls?

Mycoplasma
Ureaplasma
Chlamydia
Mycobacterium

Species of Mycoplasma and Ureaplasma

M. Pneumoniae
M. Genitalium
M. Hominis
U. Urealyticum
U. Parvum

Mycoplasma Pneumoniae
- Identification

No Cell Wall (No Gram Stain)
Coccoi
Inhibited by Antibiotics
Grows on artificial media

Mycoplasma Pneumoniae
- Infection

Symptoms
- Tracheobronchitis
- URTI
- Atypical Pneumonia

Mycoplasma Genitalium
- Identification

No Cell Walls (No Gram-Stain)
Cocci
Sexually Transmitted

Mycoplasma Genitalium
- Infections

Males: Urethritis
Females: Urethritis, Pelvic inflammatory disease

Other Genital Mycoplasmas

M. Hominis, U. Parvum, U. Urealyticum - Often appear in female GI tract without causing symptoms - Studies show that U. Urealyticum causes urethritis in males

Chlamydia Trachomatis - Identification

No Cell Wall (No Gram Stain) Intracellular Pathogen Sexually Transmitted Disease Infective Elementary Bodies --> Reticulate Bodies

Chlamydia Trachomatis - Infections

Serotype A, B, C Serotype D-K Serotype L1, L2, L3

Chlamydia Trachomatis - Serotype A, B, C

Trachoma - Chronic Conjunctivitis - Leading cause of blindness

Chlamydia Trachomatis - Serotype D-K

Genitourinary Infection - Males: Urethritis - Females: Cervicitis - Newborns: Conjunctivitis and Pneumonia

Chlamydia Trachomatis - Serotype L1, L2. L3

Lymphogranuloma Venereum - Primary: Painless papule/ulcer - Secondary: Painful enlarged lymph nodes - Tertiary: Anogenital fibrosis

Chlamydia Pneumoniae - Identification

No Cell Wall (No-Gram Stain) Sexually Transmitted Intracellular Pathogens Infective Elementary Bodies --> Reticulate Bodies

Chlamydia Pneumoniae - Infections

Similar to M. Pneumoniae - Causes Community Acquired Pneumonia - Transmitted by respiratory secretions

Chlamydia Psittaci - Identification

No Cell Wall (No Gram-Stain) Intracellular Pathogen Sexually Transmitted Infective Elementary Bodies --> Reticulate Bodies

Chlamydia Psittaci - Infection

Ornithosis or Psittacosis - Found in respiratory secretions, feces, and urine of birds - Psittacine birds are highest risk

Mycobacterium Tuberculosis - Identification

Complex Lipids in Cell Wall (Hard to Gram-Stain) Acid-Fast Bacilli Complex made up of 10 species of bacteria

Mycobacterium Tuberculosis - Infections

Pulmonary Disease 1. Bacteria is inhaled into the alveoli 2. Establishes infection 3. Formation of granulomas

Mycobacterium Leprae - Identification

Complex Lipids in Cell Walls (Hard to Gram-Stain) Acid-Fast Bacilli Complex made up of 10 species of bacteria Can not be cultured in a laboratory

Mycobacterium Leprae - Infection

Leprosy: Chronic, Granulomatous, Debilitating Disease - Skin Lesions, hypopigmentation, erythematous - Reduced Sensation, weakness, peripheral nerve thickening - Peripheral sensory nerve damage

Non-Tuberculosis Mycobacteria - Main Syndromes

1. Chronic Pulmonary Disease 2. Lymphadenitis 3. Soft Tissue Infection 4. Bone and Joint Infection 5. Disseminated Infection 6. Catheter Related Infection