Síntesis de Glucógeno Flashcards

1
Q

Glucosa –> Glucosa-6-P

A
  • Hexoquinasa (músculo esquelético y otros tejidos)
  • Glucoquinasa (hígado y células beta del páncreas)
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2
Q

Principal precursor

A

Glucosa-6-P

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3
Q

Inhibe a la Hexoquinasa

A

Glucosa-6-P

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4
Q

Activa a la Glucoquinasa

A

Fructosa-6-P

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5
Q

Glucosa-6-P –> Glucosa-1-P

A

Fosfoglucomutasa

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6
Q

¿Qué produce la reacción de Glucosa-1-P + UTP?

A

UDP-Glucosa
Enzima: UDP-Glucosa pirofosforilasa

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7
Q

Rate limiting step

A

UDP-Glucosa –> Enlaces (a-1,4) lineales en los extremos no reductores
Enzima: Glucógeno sintasa

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8
Q

Inhibe a la glucógeno sintasa

A
  • Epinefrina y Norepinefrina
  • Glucagón
  • AMPc
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9
Q

Activa a la glucógeno sintasa

A
  • Insulina
  • Cortisol
  • Glucosa-6-P
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10
Q

Ayudan la glucógeno sintasa a formar una cadena de novo

A

Glucogenina + Tirosina

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11
Q

Enzima que hace los enlaces (a-1,6) y los une a la cadena lineal para formar el GLUCÓGENO
último paso

A

Enzima ramificadora (a-1,6)
(transferasa)

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12
Q

¿V o F?

La síntesis de glucógeno también puede partir de lactato

A

Verdadero

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