signalling pathways Flashcards

1
Q

describe BMP

A

morphogen
DV pattern
smad tfs
organiser cells express antagonists

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2
Q

describe Wnt

A

morphogen
axis formation
antagonists act anteriorly

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3
Q

describe Shh

A

morphogen
limb patterning
GLI tfs

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4
Q

describe Hox

A

transcription factor
positional(hindbrain) AP

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5
Q

describe delta/notch

A

contact dependant
notch = receptor
neural cell fate if low delta notch

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6
Q

describe Ephs

A

guidance cues
boundary formation

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7
Q

describe robo

A

guidance cue
midline crossing
signalling pathway = Rho gtpases

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8
Q

describe NGF

A

growth factor
receptors are TrkA(high affinity) and p75NTR(low affinity)

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