lecture 5- neural crest formation Flashcards
what does the neural plate give rise to
CNS
what does the neural border give rise to
PNS
what is the final step of neurulation
closure of neural tube
what is the first step of neural crest formation
early border established at interface of induced neural plate surface ectoderm
what is the expression of msx due to
intermediate levels of BMP signalling
what is the second step of neural crest formation
specialised neural plate border develops with its own progenitor cells
what is neural crest identity driven by
upregulation of transcription factors in neural plate border cells
what is the 4th step of neural crest formation
TFs upregulate epithelial-mesenchynal cell transition
neural crest cells begin to migrate away
what three things are different cell types generated by
position of origin of neural crest cells
time of generation of neural crest cells
migratory pathway and signals
what do superficial neural crest cells become
pigment cells of skin
what do intermediate neural crest cells become
sensory ganglia
what do medial neural crest cells become
sympathetic ganglia/adrenal medulla
why do some cells stay as roof cells
to upregulate BMP signals so therefore more spinal cord progenitor cells
