Signal transmission 2

Question 1

what are two types of neurotransmitter receptors

Answer 1

ionotropic

metabotropic

Question 2

what are ionotropic receptors

Answer 2

ligand gated channel receptors

extrcellular domain that forms the receptor for transmitters

Question 3

what is an agonist and two examples

Answer 3

substance that binds to neurotransmitter acitons
AMPA
NMDA

Question 4

what is an antagonist

Answer 4

drugs that bind but do not activate transmitter receptors, thereby blocking actions of neurotransmitters or agonists

Question 5

what are EPSPs

Answer 5

excitatory postsynaptic potential

Question 6

how are EPSPs mediated

Answer 6

by the inflow of na and ca which leads to depolarisation and makes neuron fire

Question 7

what are IPSPs

Answer 7

inhibitory postsynaptic potnetials

Question 8

how are IPSPs mediated

Answer 8

by the outflow of k and cl

leads to hyperpolarisation

Question 9

what are metabotropic receptors

Answer 9

act solely by altering intracellular metabolic reactions and often simulate the production of second messengers- cAMP

Question 10

what are autoreceptors

Answer 10

receptors on presynaptic terminal activated by own transmitter

Question 11

what are heteroreceptors

Answer 11

receptors on presynaptic terminal not activated by their own signals