Signal Transduction Flashcards
1
Q
Cholera toxin
A
ribosylates Gsalpha; no longer hydrolyze GTP->constantly active causing Cl- secretion and H2O loss in gut lumen
2
Q
E. Coli
A
GSalpha
3
Q
Bordetella pertusis (Whooping cough)
A
CYS side chain of alpha-subunit; Gram -ve, paralyzes cilia fx of resp. epith