Signal Transduction Flashcards

1
Q

Cholera toxin

A

ribosylates Gsalpha; no longer hydrolyze GTP->constantly active causing Cl- secretion and H2O loss in gut lumen

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2
Q

E. Coli

A

GSalpha

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3
Q

Bordetella pertusis (Whooping cough)

A

CYS side chain of alpha-subunit; Gram -ve, paralyzes cilia fx of resp. epith

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