PPP Flashcards

1
Q

G6PDH deficiency

A
  • Sx:
    • Bouts of acute of haemolytic anaemia
    • Increased breakdown of erythrocytes: anaemia & jaundice
    • Lab: accumulation of breakdown products of haemoglobin in blood. Urine dark
      brown (COLA) in colour as breakdown products are excreted.
    • Heinz bodies
  • Preciptiation factors
    • All NADPH is consumed
    • AAA: Antibiotics (Sulfamethoxazole), antimalarials, antipyretics
    • Fava beans: high levels of vicine
    • Infection: respiratory burst
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