PPP Flashcards
1
Q
G6PDH deficiency
A
- Sx:
- Bouts of acute of haemolytic anaemia
- Increased breakdown of erythrocytes: anaemia & jaundice
- Lab: accumulation of breakdown products of haemoglobin in blood. Urine dark
brown (COLA) in colour as breakdown products are excreted. - Heinz bodies
- Preciptiation factors
- All NADPH is consumed
- AAA: Antibiotics (Sulfamethoxazole), antimalarials, antipyretics
- Fava beans: high levels of vicine
- Infection: respiratory burst