Sickle cell disease Flashcards

1
Q

Sickle cell inheritance pattern

A

autosomal recessive

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2
Q

pts with sickle cell have an _______x increased risk of osteomyelitis

A

100x increased risk of osteomyelitis

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3
Q

most frequently associated organism with sickle cell osteomyelitis

A

Salmonella

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4
Q

is hematopoiesis more common in sickle cell or thalassemia?

A

sickle cell

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5
Q

in advanced sickle cell why do the bones look so sclerotic?

A

multiple bone infarctions become nearly confluent and produce diffusely sclerotic bones

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6
Q

spine finding in sickel cell

A

H shaped vertebral bodies represent osteonecrosis of the endplates

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