Paget Disease

Question 1

Age distribution for Pagets

Answer 1

older

Question 2

virus possibly associated with Pagets

Answer 2

paramyxovirus

Question 3

Phases of Paget’s

Answer 3

Phase I: osteoblastic
Phase II: mixed lytic and sclerotic
Phase III: sclerotic phase

Question 4

geographic lytic skull lesion

Answer 4

osteoporosis circumscripta

Question 5

what phase is associated with cotton wool appearance

Answer 5

Phase II, mixed lytic and sclerotic

Question 6

Spine finding in Paget

Answer 6

Picture frame vertebra

Question 7

Findings in pelvic Pagets

Answer 7

asymmetric thickened and coarsened trabecula, thickening of the iliopectineal and ilioischial lines

Question 8

progression of Paget disease in long bones

Answer 8

proximal articular end to the diaphysis with a sharply demarcated border

Question 9

Paget finding commonly seen in long bones

Answer 9

blade of grass/flame shaped margin which describes the sharp margin made during Phase I of Paget in the long bone as the lytic phase progresses from the articular surface to the diaphysis

Question 10

difference between “juvenile Paget” and real Pagets

Answer 10

in Juvenile Paget (hyperphosphatemia) there is sparing of the articular ends. IN real Paget disease there is always articular involvement