shock Flashcards
distributive shock includes…
septic, anaphylactic, and neurogenic
vasodilatory/normovolemic shock
“distributive shock”
- loss in blood vessel tone leading to loss of vascular volume into the extravascular space
allergy to blood products
whole blood is the highest and albumin is the lowest
1st exposure to an allergen
Ige synthesis by B cells
2nd exposure to an allergen
Ige modulated within 15 min
Histamine
mediates allergic inflammatory response by binding to H1 on endothelial and smooth muscle cells to cause vasodilation and bronchoconstriction
increase in vascular permeability
change in osmotic pressure causing fluid to shift out of circulation leading to edema
bronchoconstriction
low pressure due to vasodilation which activates platelets releasing from mast cells
anaphylactic shock
hypoperfusion of organs and fluid shift leading towards circulatory collapse
anaphylaxis treatment
adrenergic agonist, glucocorticoids
epinephrine and dexamethasone
treatment for anaphylaxis
anaphylactic shock treatment
A- beta 2 agonist
B- oxygen
C- NS, IV adrenergics
shock
hypoperfusion of organs leading to lack of nutrients and O2 to meet demands and can result in metabolic acidosis
hypovolemic shock
low blood volume leading to decreased cardiac output due to trauma or severe dehydration
- 20% loss
cardiogenic shock
low cardiac output due to ineffective pumping of heart; causes myocardial infarction
- will present as low SBP, hypoxia, cyanosis, high JVP