basics of pathopharm Flashcards by abby wright

Q

lipophilic drugs

A

more easily absorbed and distributed

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Q

hydrophilic drugs

A

more easily excerted

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Q

absorption

A

time for drug to reach systemic circulation

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Q

therapeutic index

A

ratio between median therapeutic and toxic dose

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Q

distribution

A

transport through the body to target tissues

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Q

unbound drugs

A

effective

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Q

bound drugs

A

not effective

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Q

metabolism

A

prepares drug for excretion

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Q

primary organ of excretion

A

kidneys

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Q

Cmax

A

highest concentration of drug in blood

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Q

affinity

A

strength

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Q

efficacy

A

effectiveness

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Q

potency

A

strength

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Q

potency of 20mg vs 10mg drug

A

10mg is higher potency

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Q

confusion, hyperthermia, tachycardia, tachypnea

A

ASA toxidrome

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Q

abdominal pain, loss of appetite, nausea

A

acetaminophen toxidrome

Q

bradypnea, apnea, bradycardia, pupil constriction

A

opiate toxidrome

Q

agitation, tachypnea, tachycardia, hyperthermia

A

cocaine/stimulant toxidrome