Shigella - Exam 2

Question 1

Shigella is a gram _____ bacteria.

Answer 1

Negative

Question 2

Which genus of Shigella infects humans?

Answer 2

Shigella dysenteriae

ZOONOSIS! VERY INFECTIOUS!

Question 3

True/False. Shigella is only infectious at high doses of organisms.

Answer 3

False. Infectious dose is low (10-100 organisms)

Question 4

What are the early and late signs of a Shigella infection?

Answer 4

Early: fever, abdominal pain, water diarrhea

Late: Dysentery (hemorrhagic enteritis)

Question 5

How is Shigella transmitted?

Answer 5

Fecal-oral route

Question 6

Which toxin does S. dysenteriae produce that affects ribosome function in hose cells and causes cell death?

Answer 6

Shiga toxin

Target cells are endothelial cells in blood vessels

Question 7

True/False. Shigella may cause necrohemorrhageic peridonititis/gingivitis and arthritis.

Answer 7

True

Question 8

What is the general disease caused by Shigella bacteria?

Answer 8

Bacillary dysentery