Mycobacterium - Exam 2 Flashcards

1
Q

What is the best way to stain Mycobacterium and why?

A

Acid-fast stain

LIPID RICH CELL MEMBRANE!

Long and complex micolic acids present in cell membrane

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2
Q

True/False. Mycobacterium in anaerobic.

A

FALSE!

AEROBIC!

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3
Q

What are the important diseases caused by Mycobacterium spp.?

A

Tuberculosis

Paratuberculosis (Johne’s Disease)

Granulomatous disease

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4
Q

What is the most important virulence factor that Dr. Soto does not want us to forget about Mycobacterium?

A

LIPID RICH CELL WALL!!

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5
Q

True/False. Tuberculosis is not a reportable disease.

A

FALSE! REPORT IT!

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6
Q

How is Mycobacterium transmitted?

A

Via the respiratory and alimentary routes

MILK FROM INFECTED MAMMARY GLANDS IS A SUPER IMPORTANT WAY PEOPLE GET THIS!

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7
Q

Which species of Mycobacterium affects the respiratory tract, adjacent lymph nodes, and serous cavities?

A

Mycobacterium bovis

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8
Q

What species of Mycobacterium mainly infects swine and how?

A

M. Bovis via the alimentary route

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9
Q

Which species of Mycobacterium mainly infects cats and dogs?

A

M. Bovis

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10
Q

Primates are susceptible to which species of Mycobacterium?

A

M. bovis (via ingestion [unpastuerized milk])

M. tuberculosis (aiborne route)

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11
Q

Birds are naturally susceptible primarily to which species of Mycobacterium?

A

M. avium

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12
Q

True/False. There is no zoonosis with tuberculosis.

A

False! REVERSE ZOONOSES!

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13
Q

True/False. Tuberculosis is typically a disease of captivity and domestication.

A

True

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14
Q

Which of the following is NOT a characteristic of tubercle bacilli:

  • very hardy
  • resistant to many antimicrobial and disinfectants
  • survive short periods in soil and resist drying
A

-survive short periods in soil and resist drying

THIS IS NOT A CHARACTERISTIC OF TUBERCLE BACILLI

they survive for LONG periods in soil and resist drying

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15
Q

Which species of Mycobacterium causes Johne’s disease in cattle?

A

M. avium subsp. paratuberculosis

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16
Q

True/False. Johne’s disease is a reportable disease.

A

True! REPORT IT!

17
Q

What is the main reservoir for M. avium subsp. paratuberculosis?

A

Sympomatic and asymptomatic wild and domestic ruminants, swine and rabbits

18
Q

What is the main mode of transmission for M. avium subsp. paratuberculosis?

A

Fecal-oral

(in utero infection and ingestion of contaminated colostrum or milk are also possible routes)

19
Q

Which animals are the most susceptible to M. avium subsp. paratuberculosis? Young or old animals?

A

Young animals

20
Q

What type of stain is used for acid-fast stain?

A

Ziehl-Neelsen

21
Q

True/False. M. avium subsp. paratuberculosis has a laboratory growth dependency for mycobactin.

A

True

22
Q

The failure to eliminate the bacteria from host is due to the activation of what being compromised?

A

IFN-gamma

23
Q

Which cattle breeds are predisposed to Johne’s disease?

A

Guernsey and Jersey

24
Q

Which species of Mycobacterium causes feline leprosy?

A

M. lepraemurium

(chronic noduloulcerative-nontuberculous mycobacterial infection of the skin)

25
Q

What causes canine leproid granuloma syndrome?

A

An uncultured, saprophytic species of Mycobacterium

26
Q

What causes ulcerative dermatitis of dogs and cats?

A

rapidly growing Mycobacteria

M. fortuitum, M. chelonae

27
Q

What is bovine facry and what causes it?

A

Bovine myobacterial ulcerative lymphangitis

Caused by: M. farcinogenes and/or M. senegalenses

(nodulo-ulcerative skin lesion in cattle on the lower extremities and ventral trunk)

28
Q

Which species of Mycobacterium affects marine and freshwater organsims?

A

M. marinum

29
Q

Which species of Mycobacterium is present in tropical and temperate climates?

A

M. fortuitum

30
Q

Which species of Mycobacterium affects cold water salmonids?

A

M. chelonae

31
Q

Which of the following grows the fastest in the laboratory? M. fortuitum, M. chelonae, or M. marinum?

A

M. fortuitum and M. chelonae are grow fastor than M. marinum which is a great diagnositic tool.