Klebsiella - Exam 2 Flashcards
Klebsiella is a gram _____ bacteria.
Negative
Which virulence factor of Klebiella is responsible for fever, neutropenia, petechia and shock?
Endotoxin - lipid A
Which virulence factor is essential to Kelbsiella and binds to epithelial cells in urinary and respiratory tracts?
The capsule
What is the most common bacterial isolate from non-human primates with pneumonia?
K. pneumoniae
How is Klebsiella transmitted?
Many species it is transferred by wound infections, especially when skin or mucosae are breached by dz, trauma, burns, ect
What economincally significant disease does Klebsiella cause in ruminants?
Bovine mastitis
Case fatality as high at 80%
What diseases does Klebsiella cause in horses?
Reproductive tract disease (vaginitis, inferitilty, metritis and abortion)
Navel ill (common in animals that failed passive transfer)
What are the diseases that Klebsiella commonly causes in dogs?
Pyometra, systitis, prostatitis, meningoencephalitis, enteritis, mastitis and hepatic abcessation
What diseases does Klebsiella cause in pet birds?
Respiratory infections, septicemia and diarrhea
What diseases does Klebsiella cause in reptiles?
Pneumonia and hypopyon
(hypopyon - inflammatory cells in the anterior chamber of eye)
What does Klebsiella cause in guinea pigs?
Septicemia
What makes the bacteria more invasive and more resistant to phagocytosis?
Capsular serotypes K1 and K2 that carry genes MagA and rmpA
(MagA - mucoviscosity-associated gene/K1 specific capsular polymerase gene)
(rmpA - regulator of mucoid phenotype)
What causes septic shock with Klebsiella?
DIC
What species of monkeys in St. Kitts is Klebsiella prevalent in?
Vervet monkeys
Abscesses everywhere found in a Vervet onkey with pus present in the abdominal cavity
What is indicative of capsule ona bacteriological culture of Klebsiella?
Large mucoid viscous colonies on blood agar
