Non-Spore forming Obligate Anaerobes - Exam 2

Question 1

Which obligate anaerobe produces cytotoxin?

Answer 1

Fusobacterium necrophorum

Question 2

Which obligate anaerobe produces an enterotoxin-like entity?

Answer 2

Bacteroides fragilis

Question 3

True/False. The immune response plays a major role in resolving the pyonecrotic process involving obligative anaerobes.

Answer 3

False.

The immune response plays a MINOR role in resolving the pyonecrotic process involving obligative anaerobes.

Question 4

True/False. Non-spore forming anaerobes are part of the normal flora.

Answer 4

True

Question 5

Which toxin produced by this group of bacteria is inhibitory to polymorphnucleotides?

Answer 5

Succinic acid

Question 6

What is a key aspect to the samples taken for diagnosis of anaerobes?

Answer 6

The samples have a very repugnant odor (same for invasive clostridia)

Due to volatile fatty acid production

Question 7

What increases the chance of bacterial infection with this group?

Answer 7

Very low blood supply and low O₂supply

Question 8

Describe the “glove box” that is used to isolate this group of bacteria.

Answer 8

IMPORTANT FOR ISOLATION: reduce O₂ in environment

“glove box” - anaerobic chamber where you place your hands in gloves to be able to manipulate the samples within the chamber

Question 9

How does the general pathogensis for these obligate anaerboes work with faculative bacteria?

Answer 9

Continous synergistic inflammatory response between anaerobes and falcultative anaerobic bacteria

(capsule, cell wall, toxins, phagocytes)

Question 10

What are the common facultative organisms that are synergistic with anaerobes during infection?

Answer 10

Pasteurella and enterics in dogs/cats

Beta-hemolytic streptococci and enterics in horses

Arcanobacterium pyogenes and enterics in ruminants

**would treat for both anaerobes and facultative organisms**

Question 11

Dichelobacter is gram _____.

Answer 11

Negative

Question 12

Fusobacterium necrophorum is gram ______.

Answer 12

Negative

Question 13

Which anaerobe is a causative agent of bovine liver abcesses?

Answer 13

Fusobacterium necrophorum

Question 14

Which anaerobes are the caustive agents of foot rot? Which species is susceptible?

Answer 14

Dichelobacter nodsus and Fusobacterium nercrophorum

Contagious infectious dz affecting epidermal portions of food of sheep and goats - causes cripling lameness

Question 15

Whic anaerobe causes calf diphteria?

Answer 15

Fusobacterium necrophorum

**calf diphteria - necrotic pharyngitis or laryngitis

Question 16

Which anaerobe causes necrotic rhinitis of pigs?

Answer 16

Fusobacterium necrophorum

Question 17

Which part of the body would you swab to isolate F. necrophorum?

Answer 17

The oral cavity and gastrointestinal tract of animals

Question 18

Which anaerobe produces leukotoxin and hemagluttinin that facilitates the survival of synergistic bacteria?

Answer 18

F. necrophorum

Synergistic bacteria: D. nodsus and A. pyogenes

Question 19

How would you treat foot rot?

Answer 19

Removal and exposure of diseased tissue - hoof triming with disinfectants or antibiotics (penicillen and streptomycin)