Shah Chapter 1 Flashcards
Viruses
Obligate intracellular parasites; particles either DNA or RNA (not cells); cause diseases like flu, chicken-pox, common cold, and rabies
Microbiology
Study of small living things usually not observed w/o microscope individually
Microorganism
too small to be seen w/o magnification
microscopic
invisible to the naked eye
macroscopic
visible to the naked eye
Pathogen
any microorganism that causes disease
opportunistic pathogen
situation where nonpathogenic or weakly pathogenic microbes cause disease in a immunologically compromised host
colony
a macroscopic cluster of cells in a solid medium arising from the multiplication of a single cell
no nucleus
bacteria & viruses, viruses cannot reproduce unless in a cell
True nucleus
Protozoa, Algae, Fungi & Helminths
Protozoa
Ingests
Algae
Photosynthesis
Fungi
absorbs
Helminths
only animal causing disease
tapeworms
absorbs nutrients
roundworms
Eat intestines
Bacteria
single cell, prokaryotic, causative agent of Lyme disease
vector
transmits infectious agents from one host to another, usually biting, piercing such as tick, mosquito or fly
parasite
the organism that lives on or within the host which it obtains its nutrients and enjoys protection
Vector of Lyme Disease is a member of which group in microbiology
Animal
Secretes enzymes out of there body and into whatever host they are using, those enzymes breakdown the tissue of the host and then the organism absorbs the breakdown products, some examples of this group are single celled & multicellular
Fungi
Prokaryotic Cells
no nucleus or organelles
Eukaryotic Cells
True nucleus & mitochondria
Study of fungi
Mycology
Classification, naming, & identification of microorganisms
Taxonomy
Cleaning up environmental pollution using life forms
Bioremediation
Designing new organisms deliberately modifying genetic structure
recombinant DNA
Range of human eye
1mm
Range of Light Microscope
1 micrometer- 100 micrometer
Range of electron microscope
1 nanometer- 200 micrometer
Ubiquitous
everywhere
potential pathogen
has ability to cause problem, ecoli in gut is ok but ecoli in bladder causes uti
Normal micro biota
bacteria in certain part of the body that does not cause problem
Robert Hooke 1665
term “cell”
Antoine Van Leeuwenhoek
first observed microorganism w/ microscope he invented “father of microbiology”
Francisco Redi
Disapproved spontaneous generation
Spontaneous Generation
early belief that life can arise from vital forces present in nonliving or decomposing matter
abiogenesis
non life
Edward Jenner
Small pox vaccination
Ignaz Semmelweis
lowered the incidence of childbirth fever by making the health care workers wash their hands with chlorinated lime
Joseph Lister
“Aseptic Technique” in surgery, used phenol to treat instruments, dressings and wound to control microbial growth
Louis Pasteur
Disapproved spontaneous generation, credited for initiating “Aseptic Technique” in the laboratory, proved microbes are everywhere & can’t negotiate curves
Biogenesis
living things can only arise from other living things
Robert Koch
developed a series of experimental steps that proved that a particular microorganism caused a specific disease; studied the bacterium bacterium Bacillus anthracis, identified cause of anthrax, TB, and cholera
Angelina Hesse
Used “Agar” to culture bacteria
Hans Christian Gram
Gram stain procedure divides all bacteria into 2 possible groups based on cell wall composition
Paul Ehrlich
Father of Chemotherapy “magic bullet” target bacteria w/o harming healthy cells; instead discovered the synthetic arsenic derivative Salvarsan that was an effective tx for syphilis
Alexander Fleming
First observed the antimicrobial ability of the mold penicillium
Rebecca Lancefield
Streptococcal Classification system based on a surface antigens group A strep group B strep
Discovered ATB Streptomycin
Selman Waksman
Endosymbiotic Hypothesis, prokaryotic cell engulfed another prokaryotic cell creating a eukaryotic cell
Lynn Margulis
process of assigning names to the various taxonomic rankings of each microbial species
nomenclature; developed by Carolus Linnaeus father of taxonomy
Levels of Classification
Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species
Rules for writing scientific names
May underline or italicize, Capitalize first letter
Woese arranged organisms into 3 domains based on this criterion
rRNA sequencing
Woese classified the prokaryotes that lives in extreme environments such as in glaciers, deep see vents, and hot sulfur in
Dormain Archae
Sexual/ Asexual, Animals plants fungi protozoa algae, cell wall-plants(cellulose) fungi(chitin) animals (no), sterols, 80S, Complex, 2.0-100um, nucleus
Eukaryotes
Asexual, bacteria, no organelles, cell wall-peptidoglycan, no sterols, ribosomes 70S, simple, no nucleus, 0.5-3.0um
Prokaryotic
Members of the same genus and species that have mutated to be significantly different than other members of the species are called by this special term e.g. E.coli 0157:H7 & Influenzavirus H1N1
Strain
Bergey’s Manual of Systemic Bacteriology 2nd edition
rRNA
Term used to describe spherical bacteria arranged in pairs
Diplococci
Term used to describe rod-shaped bacteria arranged in chains
Streptobacilli
Flexible bacteria that resemble corkscrews and move by means of endoflagella (axial filaments)
Spirochete
Identification aid that contains a series of paired statements that can be used to help identify an organism
Dichotomous Key
Spherical bacteria that divide in multiple plains forming grapelike clusters are called
Staphylococci