Sexually transmitted infections Flashcards
pH change with trichomonas
pH of 5.5-6 and appearance of strawberry cervix
Chlamydia trachonatis
Genital tract and eye (gram -ve cocci)
Chlamydia pstittaci
zoonotic pneumonia (birdkeepers) - RTI
Chlamydia pneumonia
Upper and lower RTI
What are chlamydia serovars?
Variations of chlamydia - cause different AB responses
Chlamydia serovar A_C
Infects eye
Chlamydia serovar D-K
Affects genitals and eye
Chlamydia screening
- National Chlamydia Screening Programme- asymptomatic sexually active <25, reduce infection and transmission
- Contact tracing - break transmission chain, prevent re-infection
Complications of chlamydia
Infertility, ectopic pregnancy, endometritis and premature miscarriage
Causes PID which affects liver
Chlamydia infection
Chlamydia forms elementary bodies
This causes an immune response as macrophages phagocytose
IFN-Y is released
Host cells are attacked, forming reticular bodies
RBs expand and proliferate
In persistent state (not infecting), HSP60 is made
Human immune system attacks HSP60 but in doing so attacks own cells
Are reticular bodies infectious?
No but elementary bodies are
Why does chlamydia cause premature miscarriage?
Embryos make lots of HSP60
Contraindications for olfloxacin and doxycycline
Pregnancy
Which HSV is genital
1
Which HPV strains are dangerous?
6,11,16,18