SEXUALLY TRANSMITTED DISEASES Flashcards
DESCRIBE STAGES OF Shypillis
PRIMARY: begin with a painless chancre which heals after around 4-6 weeks. this is highly contagious as T.P sheds from it .
secondary; bacteria multiple and spread. you get a widespread rash which usually imvolves the soles of the feet and condyloma latum (warts) painless appear in moist places like vulva and scrotum, agian highly contagious
then latent stage - most people are asymptomatic during this phase . people can stay in this stage or progress to 3,
tertiary syphilis, comes after years, involves slow inflammatory damage to organs, tissues and small vessels. grouped 1. CVD- aneurysm 2. Gummatous syphilis 3. Neurosyphilis
conginital shyphillis
EARLY: effects are similar to secondary liver,spleen,lymph node enlargements
LATE:effects are similar to tertiary. saber shins,saddle nose,bone and teeth abnormalities hutchinson’s teeth
tests for shypillis
non specific and specific
non specific: due to cellular damage you have release of cardiolipin and lecithin-body produces AB’S against them
examples VDRL,RPR
specific: FTA
how is secondary syphilis diagnosed
serological tests
elementary and RB
EB- extracellular, infectious,ridgid outer membrane,non replicating,smaller and non metabolically active
random facts about shypillis
GRAM -
helical
motile-flagella
It’s not known to produce toxins or tissue destructive enzymes instead the disease manifestation is caused by the hosts own immune response
Very sensitive to drying and heat can’t grow on ordinary media and we have to use a dark field microscope to visualise it.
the difference chlamydia species
c. trachomatis - infects the mucous membranes such as the eyes and the vagina and lungs
c. psittatsi-only infects lungs
c. pneumonia -only infects lungs
what do we treat chlamydial infections with . ALL 3 SPECIEIS
tetracylines and erythromycin (macrolide)