antibiotics and treatments Flashcards
beta lactams and b lactaminases
penicillins, cephalosporins, cephamycins, and carbapenems.
b lactamases are enzymes that break down these antibiotics making them no longer effective, by breaking the b lactam ring open
chloramphenicol
includes use as an eye ointment to treat conjunctivitis.
it is used to treat meningitis, plague, cholera, and typhoid fever.
AMinoglycosides
like streptomycin and gentamycin
cell wall target
2 groups
b.lactams
glycopeptids
good and bad thing about b lactams
awesome to use on pregz and kids but have allergies
glycopeptides
vancomysin
teicoplanin
affecting cell membrane
polymyxins
lipopeptides
polyenes-antifungal activity
which ab’s have dual function affecting both membrane and wall
lipoglycopeptides
affecting ribosomes 50 s
MASLO macrolides amphenicols-chloramphenicol -very toxic streptoglycan- clindamycine linocsamides oxazolidiones-linezolid
affecting 30 s
ATG
aminoglycosides- side effects ototoxicity,deafness,nephrotoxic
tetracyclines-doxyclycline
glycocyclines-tigecycline
which groups are not recomemnded for pregz and kids
the group that affect ribosomes cos they can affect us tii
what do we mainly treat PPM with
cephalosporins although p.rettgeri si quite resistant and p.mirabilis is sensitive to ampicillin