Sexually transmitted diseases Flashcards
The median time between initial HIV infection and eight is how many years
10 years
AIDS is defined by an absolute CD4 count of less than how many cells
200
Signs and symptoms that suggest aids are
Oral candidiasis i.e. thrush, fever, weight loss, diarrhea, cough, so it’s a breath, purple to bluish-red bumps on the skin, and certain infections
What infection causes the most deaths in HIV
Pneumocystis jirovecii
And acute and brief illness that occurs in 50% to 80% of persons within a few weeks of exposure to the HIV virus
ACute retro viral syndrome
Is a cute retro viral syndrome infectious
Yes due to high viral load greater than 100,000 copies ML and high concentration of virus in general secretions. The initial immune response made me make mono nucleus low-grade fever, fatigue, generalized red rash, and lymphadenopathy.
What would an HIV anti-body test show with a cute retro viral syndrome
Negative possibly.
If strongly Suspect acute HIV infection, order
Polymerase chain reaction
What is the usual time to develop antibodies after HIV exposure
Three months
Is universal screening for HIV recommended
Yes
Screening test is An Elisa
HIV
Produces a malodorous vaginal discharge
BV
DNA probe is used for screening
Gonorrhea and chlamydia
RPR is used for screening
Syphilis
FTA-ABS, MHA-TP Are diagnostic test for this STI (treponema pallidum)
Syphilis
Treated with 2.4 million units of penicillin IM. This treatment is for early disease
Syphilis early
Treated with three doses of benzathine penicillin spaced out weekly intervals. Hint treatment for late or unknown duration of this disease
Syphilis later
Associated with positive whiff-amine test
BV
Confirmatory test is western blot
HIV
Treated with metronidazole 500 mg b.i.d. for seven days
BV and trichomonas
Etiologic agent is a virus
HIV, herpes and HPV
Clue cells present on saline wet mount
BV
This STD produces a discharge
HPV, gonorrhea, chlamydia, BV, herpes, trichomonas
Absent or decreased lactobacilli
BV
Wet prep used for diagnosis
Trichomonas, BV, and yeast
Treated with acyclovir, valacyclovir, and famciclovir with equal efficacy
Herpes
Trading with 2 g of metronidazole as a single dose
Trichomonas
May be associated with involuntary weight loss
HIV
Can produce rash on palms of the hands soles of feet
Syphilis
What STI is associated with a positive chandelier test
PID
What is a positive chandelier test
Tender cervical area
What STD produces a chanere
Syphilis
What STD produces vesicles on mucous membranes
Herpes type one
What are the screening test for HIV
EIA or ELISA
What is the confirmatory test for HIV
Western blot
When do you do an HIVRNA
If the screening tests are negative or if a cute retro viral syndrome is suspected
If you receive a patient that is HIV-positive what records do you need to request
Treatment history, prior drug resistance testing, virologic and immune responses to treatment
In HIV infected patients what disease progresses faster
Liver disease and it affects the choice of anti-retroviral therapy
What is a significant risk factor for reactivation of latent TB
HIV
What vaccines do HIV infected patients need annually
Pneumococcal, tetanus, hepatitis A and B, and flu
Do you administer alive or attenuated vaccine’s to HIV infected patients
No
How often do you obtain a CD4 count in an HIV infected patient
First CD4 count baseline then repeat once and usually every 3 to 4 months.
How often to check viral load and HIV infected patient
Need baseline and then every 3 to 4 months
If on ART, How long does it take for the viral load to be undetectable
Within 16 to 24 weeks of therapy
What other screening tests do HIV infected patients need
Hepatitis A, B and C, glucose and lipid panel, and STD assessment
If an HIV infected patient has a CD4 count of less than 200 what are they at risk for
Pneumocystis carinii
What is the prophylactic treatment for pneumocystis carinii with a CD4 count less than 200
TMP-SMX
What is the prophylactic treatment for pneumocystis carinii with a cd4 count less than 50
MAC
Azithromycin, clarithromycin once daily
A patient with new onset HIV would present with what symptoms
Fever, pharyngitis, nonpruritic macular skin rash, malaise, headache, lymphadenopathy
A 20-year-old male has suspected acute infection of HIV. How should he be screened?
What a western blot
Anemia, leukopenia, thrombocytopenia, involuntary weight loss, persistent diarrhea, severe chronic fatigue, dementia, peripheral neuropathy, herpes zoster, presence of opportunistic infections are all assessment findings for
Established HIV
Sexually active adult from high-risk population complains of petechial or pustular skin lesions of hands and soles, swollen, red, and tender joints in one joint such as the knee. Maybe accompanied by signs of STD i.e. cervicitis, urethritis.
Gonorrhea
Poly microbial clinical syndrome resulting from the replacement of the normal vaginal flora with high concentrations of anaerobic bacteria. Associated with multiple sex partners, new partners, douching, IUCs. Sexually associated not sexually transmitted
BV
What is the condition you are at Increased risk of acquiring STDs, UTIs, post gynecologic surgery infection, and preterm labor
Bacterial vaginosis
What are the causes of organisms of bacterial vaginosis
Prevotella, Mobiluncus, G. vaginalis, atopobium, and others
Asymptomatic in about 50% of women, profuse grayish white malodorous vaginal discharge, unpleasant, fishy, or musty vaginal odor, increased odor after intercourse, pruritus and burning of Vulvo vaginal area
Bacterial vaginosis
Homogeneous, white, discharge coating vulva/vagina, vaginal pH of greater than 4.7, fishy odor of vaginal discharge before or after addition of KOH, clue cells on Micro scopic exam, one or more epithelial cells coated with bacteria, obscuring borders
BV
How should BV this be treated
Screen for other STDs, metronidazole 500 mg b.i.d. for seven days. Avoid Sexual intercourse until after treatment. Condom use increases cure rates. Avoid douching to prevent reoccurrences. Treat symptomatic patients including pregnant patients
What medication should be avoided in pregnancy
Tinidazole As it is category C
When taking metronidazole or tinidazole what precautions need to be taken
No alcohol until 24 hours after her last dose
With recurrent bacterial vaginosis what must be ruled out
HIV
What is the most frequently reported infectious disease in the United States
Chlamydia
At what age is chlamydia most common
Less than 25 years old
What can cause PID, ectopic pregnancy, infertility, and pelvic pain
Chlamydia
Mucopurulent cervicitis, edematous, congested, friable cervix, vaginal discharge, cervical motion tenderness, dysuria/urethritis, salpingitis, proctitis, epididymitis, abnormal vaginal bleeding, pelvic pain, prostatitis are all assessment findings of
Chlamydia
How do you diagnose chlamydia
NAAT, DNA probe, culture, urine testing
Who should be screened for chlamydia and how often
Screen all sexually active females less than 25 years of age and all pregnant women. Re-screen in three months after treatment due to higher rates of reinfection. Follow up in one month if pregnant and symptoms persist they can cause reinfection
How do you treat chlamydia In a pregnant patient
Azithromycin 1 g or early times one Or amoxicillin 500 mg orally TID times seven
How do you treat a non-pregnant patient for chlamydia
Doxycycline 100 mg b.i.d. for seven days
When treating a male for chlamydia and epididymitis is involved how do you treat
Doxycycline times 10 to 14 days
When being treated for chlamydia what measures should be taken
Refrain from intercourse for seven days after treatment is completed. Referral sexual contacts in last 60 days.
A sexually-transmitted infection producing a purulent inflammation of mucous membranes. Underdiagnosed in US. Uncommon among monogamous heterosexual populations. Risks are men having sex with men, IV drug use and other high-risk behaviors
Gonorrhea
In males a finding of purulent urethral discharge, dysuria, testicular pain and some asymptomatic symptoms are assessment findings of
Gonorrhea
In females findings of asymptomatic symptoms, endocervical discharge, dysuria, Bartholin’s gland abscess, abnormal vaginal bleeding, abdominal pelvic pain, adnexal tenderness, and cervical motion tenderness are all assessment findings of
Gonorrhea