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Pharmacology > Sex hormone drugs > Flashcards

Sex hormone drugs Flashcards

1
Q

What kind of drug is mifepristone?

A

An anti-progesterone

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2
Q

What is mifepristone used for?

A

Medical abortion

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3
Q

How does the COCP effect LDL levels?

A

They decrease

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4
Q

How does the COCP effect HDL levels?

A

They increase

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5
Q

How does the COCP effect triglyceride levels?

A

They increase

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6
Q

What is the chemical component of Depo Provera?

A

Medroxyprogesterone acetate

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7
Q

How does progesterone effect LDL levels?

A

They increase

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8
Q

How does progesterone effect HDL levels?

A

They decrease

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9
Q

How does progesterone effect triglyceride levels?

A

They decrease

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10
Q

What is the oestrogen component of the combined pill?

A

ethinyl oestradiol

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11
Q

Which hormone is found in Yasmin?

A

drospirenone = a progestin

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12
Q

What kind of drug is drospirenone?

A

A progestin, found in Yasmin, which has both progesterone and anti-aldosterone effects

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13
Q

Why is there less fluid retention associated with Yasmin?

A

drospirenone has some anti-aldosterone effects and therefore helps to reduce fluid retention

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14
Q

What kind of drug is Cyproterone acetate?

A

A progestin and anti-androgen

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15
Q

What is the non-contraceptive role of Cyproterone acetate?

A

Can be used to treat hot flushes or hyper sexuality - it is an anti-androgen

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16
Q

Which progesterone is found in Femodene?

A

Gestodene

17
Q

What is Gestodene?

A

A progestin used in Femodene

18
Q

What is the indication for Ullipristal acetate?

A

Emergency contraception

Treatment of uterine fibroids (Esmya - liver functions)

19
Q

Name three types of selective oestrogen receptor modulators

A

clomiphene citrate
Tamoxifen
Raloxifene

20
Q

What kind of drug is clomiphene citrate?

A

A selective oestrogen receptor modulator

21
Q

What kind of drug is tamoxifen?

A

A selective oestrogen receptor modulator

22
Q

What are the side effects/adverse effects of clomiphene citrate?

A

Headache, hot flushes, visual disturbance
Ovarian hyperstiumulation
Hepatic inflammation
Increased risk of ovarian cancer

Pharmacology (9 decks)

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