Anti-emetics Flashcards

1
Q

Where are the vomiting receptors located in the brain?

A

Medulla oblongata

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2
Q

Which antiemetic is a 5-HT3 receptor antagonist?

A

Ondansetron

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3
Q

What is the mechanism of action for ondansetron?

A

5-HT3 receptor antagonist

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4
Q

Which antiemetic is a H1 receptor antagonist?

A

Cyclizine and promethazine

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5
Q

What is the mechanism of action for cyclizine?

A

A H1 receptor antagonist

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6
Q

What is the mechanism of action for promethazine?

A

A H1 receptor antagonist

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7
Q

What is the mechanism of action of metoclopramide?

A

A dopamine D2 receptor antagonist
5-HT3 and 4 receptor antagonist
Gastro-Prokinetic

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8
Q

Which anti-emetic can cause oculogyric crisis?

A

Metoclopramide

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9
Q

Which anti-emetic can cause hyperprolactinaemia?

A

Metoclopramide

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