Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Adrenergic receptors > Flashcards

Adrenergic receptors Flashcards

1
Q

What kind of receptor is alpha 1?

A

A Gq coupled receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What kind of receptor is alpha 2?

A

A G-inhibitory receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What kind of receptor are beta receptors?

A

G-stimulatory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where in blood vessels are adrenergic receptors located?

A

Tunica media

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What happens to the blood flow to the kidneys with sympathetic innervation?

A

It reduces - reducing urine output

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which receptor decreases blood flow to the GIT, skin and Kidneys with sympathetic innervation?

A

Alpha-1 receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which receptor increases blood flow to the muscles with sympathetic innervation?

A

Beta 2 receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which adrenergic receptors are found on the cardiovascular system?

A

Alpha 1- constriction

Beta 2 - relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the impact of sympathetic innervation on the eye?

A

Ciliaris muscle relaxes - this causes the lens to flatten due to beta 2 receptors. Pupil dilation due to contraction and therefore by alpha 1 receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the impact of sympathetic innervation on the salivary glands?

A

Beta 2 receptors - reduce water and electrolyte rich saliva and increase mucin
Alpha 1 decreases the blood flow to the salivary glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which receptors does carvedilol act on?

A

It is non-selective and therefore acts on both alpha and beta adrenergic receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which receptors does methyldopa act on?

A

Alpha 2 receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Where are alpha 1 receptors located?

A 
Blood vessels - peripheral vasoconstriction
Eyes - mydriasis (dilation)
Bladder sphincter - retention
Liver - glycogenolysis
Kidney - inhibit renin release
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which receptor causes urinary bladder sphincter constriction?

A

Alpha 1 receptor to sympathetic activation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where are alpha 2 receptors located?

A

Pre-synaptic membranes - decrease noradrenaline release

Pancreas - reduced insulin secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where are Beta 1 receptors located?

A

Heart - inc heart rate, inc AV node conduction, inc contractility
Juxtaglomerular cells - inc renin

17
Q

Where are Beta 2 receptors located?

A

Bronchiole smooth muscle - dilation
Vascular and skeletal smooth muscle - vasodilation
GI tract - muscle relaxation inhibits mobility
Uterus - muscle relaxation inhibits contraction
Pancreas - increase insulins secretion

18
Q

Where are Beta 3 receptors located?

A

Lipolysis in fat

Bladder - relaxation, retention of urine

19
Q

What kind of drug is adrenaline?

A

Non selective adrenergic agonist

Catecholamine (needs to be injected)

20
Q

What kind of drug is phenylephrine?

A

A selective alpha 1 agonist

Used for nasal congestion

21
Q

What kind of drug is clonidine?

A

A selective alpha 2 agonist

Used for withdrawal but can also treat hypertension

22
Q

What kind of drug is terbutaline?

A

A short acting beta 2 agonist (inhibits uterine contraction)

23
Q

What kind of drug is salmeterol?

A

A long acting beta 2 agonist

24
Q

What kind of drug is fometerol?

A

A long acting beta 2 agonist

25
Q

What kind of drug is migabegron?

A

A Beta 3 agonist used to treat detrusor overactivity

26
Q

How do cocaine and amphetamine work?

A

Indirect adrenergic agonists - prevent re-uptake of norepinephrine resulting in increased adrenergic acitvity

27
Q

What kind of drug is doxazosin?

A

A selective alpha 1 blocker - used for hypertension and BPH

28
Q

What kind of drug is Tamsulosin?

A

A selective alpha 1 blocker - used for BPH

29
Q

What kind of drug is propranolol?

A

A non-selective beta blocker

30
Q

What kind of drug is metoprolol?

A

B1 selective blocker

31
Q

What kind of drug is bisoprolol?

A

B1 selective blocker

32
Q

What kind of drug is atenolol?

A

B1 selective blocker

33
Q

What kind of drug is carvedilol?

A

A non-selective, Alpha 1 and beta 1 receptor antagonist

34
Q

What kind of drug is labetalol?

A

A non-selective, Alpha 1 and beta 1 receptor antagonist

35
Q

What kind of drug is prazosin?

A

Alpha 1 selective blocker

Pharmacology (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions