Session 9 - Liver Flashcards

1
Q

Why does the Liver look brown?

A

As it contains lots of mitochondria

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2
Q

What is the name of the ligament that separates the 2 lobes of the liver?

A

Falciform ligament

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3
Q

What blood vessel does blood from the GI tract travel to the liver by?

A

Hepatic portal Vein

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4
Q

What blood vessel deliverers oxygenated blood to the liver?

A

Hepatic artery

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5
Q

What blood vessel leaves the liver to return to the heart?

A

Hepatic Vein

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6
Q

Where is bile stored?

A

Gall bladder

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7
Q

What hormone causes the release of bile from the gall bladder?

A

CCK

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8
Q

What is a portal system?

A

Where blood passes through 2 capillary sets before returning to the heart

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9
Q

Name 2 portal systems in the body

A

Hepatic portal system and hypothalamo-hypophyseal portal system

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10
Q

In the hepatic portal system, where is the first capillary bed found?

A

GI tract

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11
Q

What travels in the hepatic portal Vein?

A

Water, carbohydrates, proteins, hormones, electrolytes, toxins

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12
Q

Where is ammonia broken down?

A

Liver

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13
Q

What is ammonia broken down into?

A

Urea

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14
Q

What doesn’t travel in the portal system?

A

Lipids

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15
Q

How are lipids absorbed in the digestive system?

A

They are taken into cell and processed in chylomicrons. These are then taken up by lymphatic vessels called lacteals in microvilli

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16
Q

Give 4 functions of the liver

A

Storage, bile production, detoxification, metabolism

17
Q

What molecules are produced in the liver

A

Plasma proteins(albumin), glycogen and coagulation factors

18
Q

What is stored in the liver

A

Iron, vitamin A, vitamin B12, Vitamin D, vitamin K and glycogen

19
Q

What is broken down in the liver?

A

Drugs, hormones, poisons and haemoglobin

20
Q

What type of cells are present in the liver that have a phagocytic function?

A

Kupffer cells

21
Q

Give an example of the exocrine function of the liver

A

Bile is produced and transported out via duct

22
Q

Give an example of the endocrine function of the liver

A

It produces angiotensinogen and secretes it into the blood

23
Q

What is the most common cell found in the liver

A

Hepatocytes

24
Q

What is the function of hepatocytes?

A

Involved in bile production

25
What is a sinusoid?
A tubular space for the passage of blood from the hepatic portal Vein and hepatic artery to the hepatic Vein.
26
What is different about the endothelial cells lining the sinusoid?
There are large gaps between cells
27
What is the portal triad composed of?
Bile duct, hepatic portal Vein and hepatic artery
28
What is the liver acinus?
The functional unit of the liver
29
Where are stellate cells found?
In the space of disse
30
What do stellate cells contain?
Vitamin A granules
31
What affect does cirrhosis have on stellate cells?
Lose their ability to store vitamin A and then different into myofibroblasts and start depositing collagen. The collagen can surround the central Vein causing hypertension and fill the sinusoids.
32
Where are kupffer cells found?
Lining the sinusoids