Session 10 - Respiratory System Flashcards

1
Q

What happens in inspiration?

A

Diaphragm contracts and moves down, increasing the volume of the cavity meaning that the pressure decreases so air is drawn in

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2
Q

What happens in exhalation

A

Diaphragm relaxes and the chest moves up. There is a smaller volume and increased pressure so air moves out

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3
Q

What is the name of the serous membrane lining the lungs

A

Pleural sacs

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4
Q

The are the names of the 2 membranes which make up the serous membrane

A

Outer membrane is the parietal serosa and the inner membrane is the visceral serosa

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5
Q

What is found in between the serous membranes

A

A lubricating fluid which creates surface tension and reduces friction.

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6
Q

What is the advantage of surface tension in the serous membrane

A

Prevents the lungs collapsing due the the many elastic fibres trying to recoil and shrink

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7
Q

What can the pleural cavity fill with?

A

Air (pneumothorax), blood (haemothorax), pus (empyema) or water (pleural effusion)

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8
Q

What is Boyles law?

A

When the volume of a contains increases the pressure will decrease

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9
Q

What is LaPlaces law?

A

Air will move from an area of lower pressure than higher pressure e.g air moves from a smaller lung into a larger lung as there is a smaller pressure in the larger lung

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10
Q

Why is the pressure in the intrapleural space negative

A

The recoiling of the lungs separates the membranes so that there is a large volume and so lower pressure

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11
Q

How do you drain fluid in the pleural cavity

A

Inserting a needle into an intercostal space

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12
Q

What is a pancoast tumour?

A

Tumour in the apex of the lung

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13
Q

What an pancoast tumour impinge on?

A

Brachialis plexus causing wasting of the lower arm

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14
Q

What is horners syndrome?

A

Syndrome caused by an pancoast tumour impinging in the sympathetic trunk.

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15
Q

What are the symptoms of horners syndrome?

A

Constricted pupil, droopy upper eyelid

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16
Q

Where is pseudostratified Epithelium found in the respiratory system?

A

Nasal cavity, pharynx, larynx, trachea, primary bronchi and secondary bronchi

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17
Q

Where is simple columnar epithelium found in the digestive system

A

Bronchiole and terminal bronchioles

18
Q

Where are simple cuboidal epithelial found in the respiratory system?

A

Respiratory bronchioles and alveolar ducts

19
Q

Where is simple squamous epithelium found int he respiratory system

20
Q

What 2 regions are found in the nasal cavity?

A

Non olfactory and olfactory regions

21
Q

What is found in the olfactory regions of the nasal cavity

A

Pseudostratified columnar epithelium, with no goblet cells and non-motile cilia

22
Q

What is the role of the olfactory region?

A

Detect odours

23
Q

What is the role of the vocal cords in the larynx

A

Stop foreign objects reaching the lungs and contribute to the resonance of the voice

24
Q

Which is anterior the oesophagus of the trachea?

25
What is the structure of the trachea?
Pseudostratified ciliates columnar epithelium, mucus membrane, submucosa, C shaped hyaline cartilage, adventita
26
What happens to the hyaline cartilage with age
It ossifies
27
What is secreted by the epithelium in the trachea and bronchi
Mucins, water, proteins and lysozymes
28
What disease results from hyperproliferation of goblet cells and less cilia
COPD
29
How does cystic fibrosis affect the mucus?
The CFTR in not present in apical membranes and so chloride transport is compromised. As less chloride ions move out so does less water, making the mucus more viscous which often results in infections
30
How does the cartilage of secondary and tertiary bronchi differ to the trachea
Irregular cartilage
31
What is the cartilage like in primary bronchi
Continuous ring
32
Why do bronchioles not need cartilage
Surrounding alveoli keep the lumen open
33
What potential issue can arise due tot the lack of cartilage in bronchioles
Excessive smooth muscle contraction (bronchoconstriction) causes difficulty in expiration. This is asthma
34
What are Clara cells
Cells which secrete a surfactant lipoprotein which prevents walls sticking together during expiration. Also secrete a Clara cell protein
35
Where are Clara cells found
Bronchioles
36
What are supporting the alveoli walls
Elastic and reticular fibres
37
What 2 types of cell compose the alveoli
Type I and II pneumocytes
38
What is the function of type I pneumocytes
The simple squamous cells permit gas exchange
39
What is the function of type II pneumocytes
These cuboidal cells produce surfactant
40
What third type of cell are also found in the alveoli
Macrophages
41
What is pneumonia
Inflammation of the lungs caused by the presence of bacteria
42
What is emphysema
The destruction of the alveoli walls creating permanent air spaces