Session 10 - Respiratory System Flashcards

1
Q

What happens in inspiration?

A

Diaphragm contracts and moves down, increasing the volume of the cavity meaning that the pressure decreases so air is drawn in

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2
Q

What happens in exhalation

A

Diaphragm relaxes and the chest moves up. There is a smaller volume and increased pressure so air moves out

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3
Q

What is the name of the serous membrane lining the lungs

A

Pleural sacs

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4
Q

The are the names of the 2 membranes which make up the serous membrane

A

Outer membrane is the parietal serosa and the inner membrane is the visceral serosa

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5
Q

What is found in between the serous membranes

A

A lubricating fluid which creates surface tension and reduces friction.

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6
Q

What is the advantage of surface tension in the serous membrane

A

Prevents the lungs collapsing due the the many elastic fibres trying to recoil and shrink

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7
Q

What can the pleural cavity fill with?

A

Air (pneumothorax), blood (haemothorax), pus (empyema) or water (pleural effusion)

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8
Q

What is Boyles law?

A

When the volume of a contains increases the pressure will decrease

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9
Q

What is LaPlaces law?

A

Air will move from an area of lower pressure than higher pressure e.g air moves from a smaller lung into a larger lung as there is a smaller pressure in the larger lung

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10
Q

Why is the pressure in the intrapleural space negative

A

The recoiling of the lungs separates the membranes so that there is a large volume and so lower pressure

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11
Q

How do you drain fluid in the pleural cavity

A

Inserting a needle into an intercostal space

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12
Q

What is a pancoast tumour?

A

Tumour in the apex of the lung

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13
Q

What an pancoast tumour impinge on?

A

Brachialis plexus causing wasting of the lower arm

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14
Q

What is horners syndrome?

A

Syndrome caused by an pancoast tumour impinging in the sympathetic trunk.

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15
Q

What are the symptoms of horners syndrome?

A

Constricted pupil, droopy upper eyelid

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16
Q

Where is pseudostratified Epithelium found in the respiratory system?

A

Nasal cavity, pharynx, larynx, trachea, primary bronchi and secondary bronchi

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17
Q

Where is simple columnar epithelium found in the digestive system

A

Bronchiole and terminal bronchioles

18
Q

Where are simple cuboidal epithelial found in the respiratory system?

A

Respiratory bronchioles and alveolar ducts

19
Q

Where is simple squamous epithelium found int he respiratory system

A

Alveoli

20
Q

What 2 regions are found in the nasal cavity?

A

Non olfactory and olfactory regions

21
Q

What is found in the olfactory regions of the nasal cavity

A

Pseudostratified columnar epithelium, with no goblet cells and non-motile cilia

22
Q

What is the role of the olfactory region?

A

Detect odours

23
Q

What is the role of the vocal cords in the larynx

A

Stop foreign objects reaching the lungs and contribute to the resonance of the voice

24
Q

Which is anterior the oesophagus of the trachea?

A

Trachea

25
Q

What is the structure of the trachea?

A

Pseudostratified ciliates columnar epithelium, mucus membrane, submucosa, C shaped hyaline cartilage, adventita

26
Q

What happens to the hyaline cartilage with age

A

It ossifies

27
Q

What is secreted by the epithelium in the trachea and bronchi

A

Mucins, water, proteins and lysozymes

28
Q

What disease results from hyperproliferation of goblet cells and less cilia

A

COPD

29
Q

How does cystic fibrosis affect the mucus?

A

The CFTR in not present in apical membranes and so chloride transport is compromised. As less chloride ions move out so does less water, making the mucus more viscous which often results in infections

30
Q

How does the cartilage of secondary and tertiary bronchi differ to the trachea

A

Irregular cartilage

31
Q

What is the cartilage like in primary bronchi

A

Continuous ring

32
Q

Why do bronchioles not need cartilage

A

Surrounding alveoli keep the lumen open

33
Q

What potential issue can arise due tot the lack of cartilage in bronchioles

A

Excessive smooth muscle contraction (bronchoconstriction) causes difficulty in expiration. This is asthma

34
Q

What are Clara cells

A

Cells which secrete a surfactant lipoprotein which prevents walls sticking together during expiration. Also secrete a Clara cell protein

35
Q

Where are Clara cells found

A

Bronchioles

36
Q

What are supporting the alveoli walls

A

Elastic and reticular fibres

37
Q

What 2 types of cell compose the alveoli

A

Type I and II pneumocytes

38
Q

What is the function of type I pneumocytes

A

The simple squamous cells permit gas exchange

39
Q

What is the function of type II pneumocytes

A

These cuboidal cells produce surfactant

40
Q

What third type of cell are also found in the alveoli

A

Macrophages

41
Q

What is pneumonia

A

Inflammation of the lungs caused by the presence of bacteria

42
Q

What is emphysema

A

The destruction of the alveoli walls creating permanent air spaces