Session 9- Embryology of the Urinary system

Question 1

from what mesderm doe sthe urinary system develop from

Answer 1

intermediate mesoderm

Question 2

step 1

Answer 2

development of pronephros
-pronephric duct extends from the cervical region to the cloaca and drives the development of the next developmental stages

Question 3

step 2

Answer 3

mesonephric tubules develop caudal to the pronephric region

Question 4

what makes up the embryonic kidney

Answer 4

mesonephric tubules plus mesonephric duct

Question 5

step 3

Answer 5

undiffernetiated intermediate mesoderm, caudal to the mesonephros

ureteric bud induces development of the true kidney, metanephros in this tissue

Question 6

how does the renal functional unit develop

Answer 6

ureteric bud drives the development of the definitive kidney

• the collecting system is derived from the ureteric bud itself
• the excretory component derived from intermediate mesoderm under the influence of the ureteric bud

Question 7

how does the urogenital sinus develop in females

Answer 7

mesonephric duct reach urogential sius

uretic bud sprouts from mesonephric duct

urogenital sinus begins to expand mesoneohric duct begins to regress

mesonephric duct regression continues, ureteric bud opens into urogenital sinus

Question 8

how does the UGS form in males

Answer 8

MD reach UGS

UB sprouts from MD

smooth muscle begins to appear UGS begins to expand

UBs and MDs make independant openings in UGS

Question 9

what does the urogenital sinus develop into

Answer 9

majority into bladder - superiorly - connectes to umbilicus

inferior part develops into urethra

Question 10

what embryological derivative is the bladder

Answer 10

hindgut