Session 8- Lower Respiratory Tract Infection and Pneumonia Flashcards

1
Q

what is acute bronchitis

A

inflammation of the large airwats of the lung- bronchi

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2
Q

what is bronchectasis

A

permanent dilation and thickening of the airways associated with chronic cough, sputum production, bacterial colonisation and recurrent infection

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3
Q

what is broncholitis

A

a viral infection of the bronchiole, the smallest air passages in the lungs. Most commonly caused by resp syncytial virus and most commonly occurs in children

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4
Q

what is empyema

A

collection of pus in the pleural cavity associayed with pneumonia but may also develop after thoracic surgery or trauma

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5
Q

what is a lung abcess

A

localised collection of pus within the lung that leads to cavity formation usually with a thich wall, radiological imaging typically demonstrates the presence of air-fluid levels in the cavity

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6
Q

when to abcesses most commonly occur

A

when microbial infection causes necrosis of the lung parenchyma, if they communicate with an airway they may lead to a purulent cough

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7
Q

what is an air fluid level

A

when air rises above a fluid in a contained space and there is a flat surface at the ‘air-fluid’ interface

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8
Q

what is pneumonia

A

inflammation of the lung parenchyma due to infection

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9
Q

what is a common feature of pneumonia

A

cellular exudate in alveolar spaces

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10
Q

what 2 ways pneumonia present

A

lobar

bronchopneumonia

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11
Q

what is the most common causative ogranism in CAP

A

streptococcus pneumonia- gram positive coccus in chains

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12
Q

what is CAP less commonly caused by

A

haemophilus influenzae
moraxela catarrhalis
group A streptococci
staph aureus

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13
Q

what atypical mictorganisms cause CAP

A

mycoplasma pneumoniae
chlamydia pneumonae
legionella pneumophilia

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14
Q

what is a nosocomial or hospital acquired pneumonia defined as

A

infection of the lower resp tract in hospitalised patients occuring >48 hours after admission

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15
Q

what are important causative organisms of hospital acquired pneumonia

A
Pseudomonas aueroginosa 
Escherichia coli
klebisella pneumoniae
acinetobacter species
staph aureus
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16
Q

when is aspiration pnemonia more likely

A

individuals whose level of consciousness is altered due to anaesthesia, alcohol, drug abuse or have swallowing-related problems

17
Q

causative agesnt fo aspiration oneumonia

A

oral flora
anaerobes
pseudomonas aeruginosa

18
Q

what organisms are individuals with a poor immune system susceptible to

A

pneumocystis jiroveci
aspergillus spp
cytomegalovirus

19
Q

clinical features pneumonia

A

malasie
fever
cough productive of sputum which may be purulent or rusty coloured

20
Q

what is a dry cough that doesnt resolve with time be indicatie of

A

atypical pneumonia caused by mycoplasma pneumoniae or chlamydia pneumoniae

21
Q

what are yhe new focal chest signs in CAP

A
crackles
decreased breath sounds
dullness to percussion
wheeze 
increased vocal resonance over area consolidation
22
Q

what is the CURB 65 score

A

assessed severity of pneumonia

C- new mental confusion
U- urea
R-resp rate
B- blood pressure

used to decide whether to hospitilisse or not

23
Q

what antibitiocs are used in hospital acquired pneumonia and why

A

Iv co-amoxiclav a yjis will cover gram negative organisms which are the most likely causative agent

24
Q

what does the URT consist of

A

nasal cavity
pharynx
larynx

25
Q

what does the lower resp tract consist of

A

trachea
bronchi
terminal bronchioles

26
Q

what does the resp zone consist of

A

resp bronchioles

alveolar ducts and alveoli

27
Q

how might a patient with pulmonary TB also develop TB in the gut

A

patients may deve;op TB if they have active TB and cough uo some MTB which is then swallowed but MTB is resistant to stomach acid

Haematogenous spread to gut

via lymphatic system