Session 6- Infections of the Reproductive Tract Flashcards

1
Q

What is the microbe that causes chlamydia

A

Chlamydia trachomatis

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2
Q

What is the most common STI n the UK

A

Chlamydia trachomatis

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3
Q

What microbe causes Gonorrhoea

A

Neisseria gonorrhoeae

-gram negative diplococcus

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4
Q

What does gonorrhoea cause

A

Thick yellow, discharge and dysuria

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5
Q

What is NGU

A

Non-gonococcal urethritis

  • inflammation of the urethra with associated discharge
  • can be pathogen negative
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6
Q

What pathogens can cause NGU

A

Chlamydia trichomatis
Mycoplasma genitalium
Trichomonas vaginalis

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7
Q

How do we investigate sti

A

Urine sample

Urethral swab- usually gonorrhoea

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8
Q

When do women get physiological discharge

A

Secretory phase - post ovulation to prevent further fertilisation

  • thicker cervical mucus
  • cyclical
  • No other associated symptoms
  • clear
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8
Q

Symptoms of C. Trachomatis in women

A

Discharge
Post-coital bleeding
Dyspareunia

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8
Q

Symptoms of C. Trachomatis in women

A

Discharge
Post-coital bleeding
Dyspareunia

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8
Q

What pathogen causes trichomoniasis

A

Trichomonas vaginalis

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8
Q

Why does tricomonas vagina is thrive in the vagina

A

Vagina pH - increased alkalinity of vagina favours acquisition of disease

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8
Q

How do we treat trichomoniasis

A

Metronidazole

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8
Q

What is the normal flora in vagina

A

Lactobacillus

-produces lactic acid to keep vagina acid and healthy

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8
Q

What causes bacterial vaginosis

A

Gardnerella baginalis

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8
Q

How do we investigate chlamydia

A

Vulvo-vaginal swabs and endocervical swabs

8
Q

How can we investigate Gonorrhoea in women

A

VVS endocervial swab

8
Q

How do we investigate Trichomoniasis

A

High vaginal swab - poster for nix

8
Q

How do we investigate BV

A

High vaginal swab, gram staining , KOH test

8
Q

Honestly do we investigate candida

A

HVS, Microsocopy > culture

9
Q

What causes vaginal discharge - infective

A

N. Gonorrhoeae
C. Trachomatis
T. Vaginalis

10
Q

What causes vaginal discharge - non sexually transmitted

A

Bacterial vagnosis

Candidiasis

11
Q

What types of HPV cause the majority of genital infections

A

6 and 11

12
Q

Which types of HPV have the highest association with cervical cancer

A

16 and 18

13
Q

What does HPV cause

A

Genital or cutaneous warts

14
Q

What is HSV-1 associated with

A

Cold sores

15
Q

What is HSV-2 associated with

A

More likely to become infected with HIV

16
Q

How do we investigate Herpes simplex

A

Check all areas

  • Anus
  • mouth
  • genial

Swabs- PCR/ NAATs

17
Q

How can we manage herpes slimed virus

A

Antivirals

  • cant eradicate the infection
  • reduce the severity and duration of current episode
  • limited effect frequency/ severity of repeated episodes
18
Q

What pathogen causes syphillis

A

Treponema pallidum

19
Q

How is syphillis transmitted

A

Direct contact

Vertical

20
Q

Primary syphillis

A

Typically painless ulcer

21
Q

Secondary syphillis

A

4-10 weeks after initial infection

Multi system- kidney, liver , rash, neonatal symptoms

22
Q

What is PID

A

Infection of teh uterus, Fallopian tubes and ovaries due to ascending infection

23
Q

whaT microbes causes pID

A

Chlamydia trachomatis
Neisseria gonorrhoeae
Gardnerella sp

24
Q

Symptoms of PID

A

Lower abdominal pain
Dyspareunia
Purelent discharge
A do real uterine bleeding

25
Q

Signs of PID

A

Pyrexia
Pain on palpitation
Discharge

26
Q

Complications of PID

A

Chronic pelvic pain
Pelvic abcess

Subferitility

  • adhesions from chronic inflammation
  • increased risk of ectopic pregnancy
27
Q

Management of PID

A

Prevention > cure

Antibiotics
Anagelsa
Screening