Session 2- Epithelial Tissue Flashcards

1
Q

What are the 4 basic tissue types?

A

Epithelial
Nervous
Muscle
Connective

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2
Q

What functions are epithelial tissues important for?

A
Protection
Excretion
Secretion 
Sensory 
Absorption 
Lubrication
Reproduction 
Cleansing
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3
Q

True or false: Epithelia are vasculated

A

False- they are avasculated and rely on surrounding blood vessels that lie close to the BM to supply nutrients and oxygen

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4
Q

True or false: Epithelia are innervated

A

True- they have a nerve supply

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5
Q

There are three types of epithelia. What are they?

A

Simple epithelia
Stratified epithelia
Glandular epithelia

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6
Q

Simple epithelia can be further divided into three types, what are they?

A

Simple squamous
Simple cuboidal
Simple columnar

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7
Q

The basement membrane is made up of two fused layers. What are they?

A

Basal lamina

Reticular lamina

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8
Q

Name three apical specialisations

A

Villi
Cilia
Sterocilia

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9
Q

How are adjacent epithelial cells held together?

A

Tight junctions

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10
Q

Tight junctions create a (1)________ which is selective for (2)_________ and (3)__________. They divide the cell into two distinct regions: (4)__________ & (5)__________.

A

(1) barrier
(2) water
(3) solutes
(4) apical
(5) basal

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11
Q

What three function do tight junctions provide in epithelial cells?

A

Functional polarity
Regulation
Leakiness

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12
Q

What structures are responsible for direct communication between cells?

A

Gap junctions

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13
Q

Gap junctions communicate both ____________ and ____________

A

Chemically

Electrically

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14
Q

What are the two structures used to attach epithelial cells to the basement membrane?

A

Focal Adhesions

Hemidesmosomes

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15
Q

Focal adhesions and hemidesmosomes both use _____________ to to achieve their function.

A

Integrins

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16
Q

Focal adhesions link the _____________ to the ______ _______________ of cells for structural strength

A

Extracellular matrix

Actin cytoskeleton

17
Q

Besides providing structural support, focal adhesions are also sites of _________ ______________.

A

Signal transduction

In response to adhesion

18
Q

Focal adhesions play a prominent role in

1) providing structural strength
2) signal transduction
3) __________________

A

Cell migration in wound repair

19
Q

Hemidesmosomes link (1)_____________ outside of the cell with (2)___________ ______________ (_____________) in the cell. This provides the cells with (3)__________________. They are found in tissues subject to (4)_______________.

A

(1) The extracellular matrix
(2) Intermediate filaments (Keratin)
(3) Structural support
(4) Abrasion

20
Q

Describe the role of desmosomes?

A

To strengthen connections between adjacent cells in epithelia that needs to withstand high mechanical stress.

21
Q

Give an example of where desmosomes may be important

A

Urinary bladder transitional epithelium

22
Q

What are the main roles of integrins (3 roles)?

A

Attachment of cells to the ECM
Signal Transduction
Immune patrolling/ cell migration

23
Q

List 5 types of cell communication

A
Autocrine 
Paracrine
Endocrine 
Synaptic
Neurocrine
24
Q

Autocrine communication =

A

Communication with self

25
Q

Paracrine communication=

A

Communication with adjacent cells

26
Q

Endocrine communication=

A

Communication via hormonal secretion

27
Q

Synaptic communication=

A

Communication via neurotransmitters

28
Q

Neurocrine communication=

A

Communication via select molecules to nearby cells with receptors on

29
Q

Cultured cells have a ____________ life span and therefore demonstrate ________________

A

Limited

Senescence

30
Q

Name two methods of cell death

A

Apoptosis

Necrosis

31
Q

Give three types of cell renewal and where in the body that type of renewal may be demonstrated.

A

(1) STATIC - CNS, heart, skeletal muscle cells
(2) STABLE- Fibroblasts, endothelium, smooth muscle cells
(3) RENEWING- Blood, skin epithelium, gut epithelium