Serotonin & Dopamine Flashcards
5-HTP
Indication - Depression
Mechanism of action - 5-HT precursor
Buspirone
Indication - Anxiety, depression
Mechanism of action - 5-HT1A partial agonist
Side effects - Early increase in anxiety
Sumatriptan
Indication - Migraine
Mechanism of action - 5-HT1D agonist
Side effects - Coronary vasoconstriction
Risperidone
Indication - Depression, psychosis
Mechanism of action - 5-HT2A/2C antagonist
Side effects - Weight gain/akathisia
Odansetron
Indication - Chemotherapy-induced emesis
Mechanism of action - 5-HT3
Fluoxetine
Indication - Depression, OCD, anxiety, panic disorder, PTSD, social phobia
Mechanism of action - SSRI
Side effects - Sexual dysfunction, insomnia
Sertraline
Indication - Depression, OCD, anxiety, panic disorder, PTSD, social phobia
Mechanism of action - SSRI
Side effects - Sexual dysfunction, insomnia
Bromocriptine
Indication - Parkinson’s disease
Mechanism of action - D2 agonist
Selegiline
Indication - Parkinson’s disease
Mechanism of action - MAO-B inhibitor
Tolcapone
Indication - Parkinson’s disease
Mechanism of action - COMT inhibitor
Metaclopramide
Indication - Nausea
Mechanism of action - D2 antagonist
Side effects - Akathisia
Haloperidol
Indication - Psychosis
Mechanism of action - D2 antagonist
Side effects - Extra-pyramidal motor disturbances
Trazadone
Indication - Anxiety, depression
Mechanism of action - 5-HT2A/2C antagonist + SSRI
Side effects - Suicidality early after initiation