Serotonin & Dopamine Flashcards

1
Q

5-HTP

A

Indication - Depression

Mechanism of action - 5-HT precursor

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2
Q

Buspirone

A

Indication - Anxiety, depression
Mechanism of action - 5-HT1A partial agonist
Side effects - Early increase in anxiety

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3
Q

Sumatriptan

A

Indication - Migraine
Mechanism of action - 5-HT1D agonist
Side effects - Coronary vasoconstriction

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4
Q

Risperidone

A

Indication - Depression, psychosis
Mechanism of action - 5-HT2A/2C antagonist
Side effects - Weight gain/akathisia

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5
Q

Odansetron

A

Indication - Chemotherapy-induced emesis

Mechanism of action - 5-HT3

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6
Q

Fluoxetine

A

Indication - Depression, OCD, anxiety, panic disorder, PTSD, social phobia
Mechanism of action - SSRI
Side effects - Sexual dysfunction, insomnia

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7
Q

Sertraline

A

Indication - Depression, OCD, anxiety, panic disorder, PTSD, social phobia
Mechanism of action - SSRI
Side effects - Sexual dysfunction, insomnia

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8
Q

Bromocriptine

A

Indication - Parkinson’s disease

Mechanism of action - D2 agonist

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9
Q

Selegiline

A

Indication - Parkinson’s disease

Mechanism of action - MAO-B inhibitor

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10
Q

Tolcapone

A

Indication - Parkinson’s disease

Mechanism of action - COMT inhibitor

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11
Q

Metaclopramide

A

Indication - Nausea
Mechanism of action - D2 antagonist
Side effects - Akathisia

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12
Q

Haloperidol

A

Indication - Psychosis
Mechanism of action - D2 antagonist
Side effects - Extra-pyramidal motor disturbances

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13
Q

Trazadone

A

Indication - Anxiety, depression
Mechanism of action - 5-HT2A/2C antagonist + SSRI
Side effects - Suicidality early after initiation

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