Adrenergic Agonists & Antagonists Flashcards
Epinephrine
Indication - Anaphylaxis, shock, cardiac arrest, heart block
Mechanism of action - Alpha and beta agonist
Norepinephrine
Indication - Acute hypotension due to shock
Mechanism of action - Alpha-agonist, beta1-agonist
Dopamine
Indication - Cardiogenic shock
Mechanism of action - Dopamine and adrenergic receptor agonist (beta-agonist, some alpha-agonist activity)
Side effects - Hypotension (low dose), tachycardia
Isoproterenol
Indication - Transient heart block
Mechanism of action - Beta-agonist
Dobutamine
Indication - Short term Rx for low cardiac contractility
Mechanism of action - Beta1-agonist
Terbutaline
Indication - Prevent and reverse bronchospasm in asthma, bronchitis, and emphysema
Mechanism of action - Beta2-agonist
Albuterol
Indication - Bronchial SM relaxation
Mechanism of action - Beta2-agonist
Phenylephrine
Indication - Pressor agent for anesthesia, nasal congestion, dilate pupil for eye exam, supraventricular tachycardia
Mechanism of action - Alpha1-agonist
Clonidine
Indication - Hypertension
Mechanism of action - Alpha2-agonist
Amphetamine
Indication - ADHD
Mechanism of action - Indirect sympathomimetic
Methylphenidate
Indication - ADHD
Mechanism of action - Indirect sympathomimetic (dopamine reuptake inhibitor)
Side effects - Tachycardia
Ephedrine
Indication - Pressor agent with anesthesia
Mechanism of action - Indirect sympathomimetic
Pseudo-ephedrine
Indication - Nasal decongestion
Mechanism of action - Indirect sympathomimetic
Propranolol
Indication - Hypertension, angina due to atherosclerosis, MI
Mechanism of action - Beta-blocker
Timolol
Indication - Glaucoma
Mechanism of action - Beta-blocker