Local Anesthetics

Question 1

Cocaine

Answer 1

Mechanism of action - vasoconstriction, rapid onset
Side effects - hypertension, tachycardia (blocks reuptake of NE)
Other - topical, ester

Question 2

Procaine

Answer 2

Mechanism of action - infiltration, nerve block, spinal anesthesia, short duration of action
Other - ester

Question 3

Tetracaine

Answer 3

Mechanism of action - spinal anesthesia, long-lasting

Other - potent ester

Question 4

Benzocaine

Answer 4

Indication - Wounds, ulcerated surfaces

Other - topical, ester of PABA

Question 5

Lidocaine

Answer 5

Mechanism of action - Infiltration, nerve block, intravenous-regional, epidural, spinal; rapid onset
Other - prototypical LA, amide

Question 6

Mepivacaine

Answer 6

Mechanism of action - Infiltration, nerve block, epidural; rapid onset
Other - amide

Question 7

Bupivacaine

Answer 7

Indication - postoperative analgesia, labor
Mechanism of action - epidural, infiltration, nerve block, spinal, prolonged duration of action
Other - potent amide, cardiotoxic

Question 8

Ropivacaine

Answer 8

Indication - labor
Mechanism of action - epidural, long-lasting
Other - amide