seronegative arthritis

Question 1

spondyloarthropathies are associated with

Answer 1

HLA-B27

NO RF, anti-CCP, ANA

Question 2

Ankylosing Spondylitis is seen in this age group

Answer 2

• late teens, early 20s commonly male
• Begins in sacroiliac joints and spreads slowly upwards
• bamboo spine
• leads to joints fusing together

Question 3

MC extraarticular manifestation of ankylosing spondylitis is

Answer 3

• uveitis

- also peripheral enthesitis at achilles common

Question 4

criteria for inflammatory back pain <50

Answer 4

(1)a history of inflammatory back pain
(2)limitation of motion of the lumbar spine in both the sagittal and frontal planes
(3)limited chest expansion
(4)definite radiographic sacroilitis
Must have criteron 4 plus any one of the other three criteria

Question 5

ankylosing spondylitis tx

Answer 5

• indomethacin
• sulfasalazine
• anti-TNF

Question 6

when is sx required for ankylosing spondylitis

Answer 6

severe hip joint arthritis

Question 7

reactive arthritis aka Reiter syndrome is characterized by

Answer 7

-a prior GI/GU infection
-Arthritis
-Urethritis
-Conjunctivitis
can’t see, pee, climb a tree

Question 8

acute onset asymmetric arthritis think

Answer 8

Reiter’s
Dactylitis (sausage digit)-Diffuse swelling of a solitary finger or toe
Enthesitis-Achilles/Plantar insertion on the calcaneous

Question 9

what to do if you think Reiter’s

Answer 9

Throat, stool, or urogenital tract cultures can be performed in an attempt to isolate the causative organism
RF and ANA are negative

Question 10

how to treat Reiter’s

Answer 10

• NSAIDs
• corticosteroids
• Anbx only for chlamydia infection, tetracycline

Question 11

psoriatic arthritis

Answer 11

• An inflammatory arthritis associated with psoriasis and a negative rheumatoid factor
• Unlike RA, it involves DIP, spine and sacroiliac jts.
• psoriasis usually preceeds arthritis

Question 12

common PE findings for psoriatic arthritis

Answer 12

• nail changes in fingers/toes

- dactilitis

Question 13

5 patterns of psoriatic arthritis invovlment

Answer 13

Asymmetrical oligoarticular arthritis 
Symmetrical polyarthritis 
Distal interphalangeal arthropathy 
Arthritis mutilans 
Spondylitis with or without sacroiliitis

Question 14

common radiographical finding in psoriatic arthritis

Answer 14

DIP involvement

“pencil-in-cup” deformity

Question 15

psoriatic arthritis treatment

Answer 15

• NSAIDs

- methotrexate