Arthritis w/systemic diseases Flashcards
how to treat hemochromatosis?
phlebotomy
sickle cell
acute vaso-occlusive episodes affecting the bones of the spine and long bones.
Painful crises then ensue, possibly ischemic necrosis
decrease of both bone matrix and mineral
osteoperosis
decrease of bone mineral but matrix is intact
osteomalacia
osteopenia
decreased bone density
what is happening in metabolic bone disease?
Rate of bone formation is normal, whereas the rate of bone resorption is increased. Therefore, the amount of bone decreases to a level where it is incapable of maintaining the integrity of the skeleton.
best imaging for maetbolic bone disease?
DEXA scan
what bone density score indicates osteoperosis?
osteopenia
- 2.5 or below
- 1.0 to -2.5
good SERM for bone density?
raloxifene
another treatment option to increase bone density?
Inhibit bone resorption, increase bone mineral density
All can cause osteonecrosis of the jaw
“ate”
other med option to increase bone density?
- denosumab
- calcitonin
- teriparatide (not first line)