serological tests for im Flashcards
infectious mononucleosis is also known as
pfeiffer’s disease or kissing disease
self-limiting acute disease affecting the lymphoid tissues
IM
IM is caused by the __ which is a __ (rna/dna) virus thatt belongs to the __ family
epstein barr virus, dna, herpesviridae
blood smear of an infected patient will exhibit the presence of enlarged atypical lymphocytes called
downey cells
im reagent contains __
stabilized horse RBCs
positive
negative
classic serologic test for the detection of heterophile antibodies against forssman antigen and serum sickness and antibodies associated with IM
paul-bunnell test (presumptive test)
__ intrinsically express different heterophile antigens such as forssman antigen, serum sickness antigen, and antigens associatied with IM
sheep RBCs
PB titer
1:56
presumptive PB titer
1:224
if the antibody titer is 1:56 or higher - (positive/negative)
positive
classic serologic test used to distinguish the different heterophile antibodies detected in the PB test
davidsohn differential test
davidsohn differential test differentiates the three types of heterophile antibodies based on their absorption patterns with __ and/or __ and their demonstration of reducing antibody titer after adding sheep RBCs or horse RBCs
guinea pig kidney cells, beef erythrocytes
IM
IM
SS/forssman
SS
forssman
forssman
rapid differential test for the serological detection of IgM class heterophile antibodies associated with IM
monospot test
monospot test is similar with PB except it utilizes __ since it has a reactive antigenic against IM and forssman antibodies
horse rbcs
