sepsis

Question 1

a clinicl syndrome characterized by systemic inflammatory response to an infectious process

Answer 1

sepsis

Question 2

what does SIRS stand for?

Answer 2

systemic inflammatory response syndrome

Question 3

SIRS is defined as having 2 out of 4 of what criteria?

Answer 3

1. temp
2. HR
3. RR
4. WBC

Question 4

SIRS temp >___ or under___

Answer 4

temp >38 (101.4) or under 36 (98.6)

Question 5

SIRS HR >____

Answer 5

90

Question 6

SIRS RR>_____ or PaO2 under____

Answer 6

RR> 20; PaCO2 under 32

Question 7

SIRS WBC >____, under____, or bandemia >____

Answer 7

WBC> 12K, under 4K, or bandemia >10%

Question 8

2/4 SIRS criteria + suspected or identified infxn

Answer 8

sepsis

Question 9

sepsis with evidence of organ dysfxn

Answer 9

severe sepsis

Question 10

liver failure can be defined as bilirubin >_____

Answer 10

4

Question 11

kidney failure can be defined as Cr >____

Answer 11

2

Question 12

sepsis and hypotension despite adequate fluid resuscitation

Answer 12

septic shock

Question 13

in the case of sepsis, should you start tx before or after blood cultures

Answer 13

start Abx after obtaining cultures

Question 14

most common gram+ isolates in sepsis (2)

Answer 14

staph aureus

strep pneumo

Question 15

most common gram- isolates in sepsis (2)

Answer 15

E coli

pseudomonas

Question 16

goals of tx in sepsis

Answer 16

MAP 65

Question 17

initial fluid of choice for management of sepsis

Answer 17

crystalloids (NS or lactated ringer)

Question 18

amt of crystalloids to initially give

Answer 18

30 mL/Kg

Question 19

if septic shock, next step in tx?

Answer 19

NE

Question 20

within 3 hours of presentation, need to have done what for management of sepsis (4)

Answer 20

1. lactate levels
2. blood cultures
3. broad spectrum Abx
4. crystalloids

Question 21

within 6 hours of presentation, need to have done what for management of sepsis (3)

Answer 21

1. vasopressors if fluid resuscitation fails
2. reassess volume status, tissue perfusion
3. re-assess lactate

Question 22

how long do you have to start Abx in septic patient

Answer 22

start within 1 hr