Sepsi

Question 1

SIRS

Answer 1

• FEBBRE > 38 o < 36
• FR > 20
• Linfocitosi ( >12.000) o Linfopenia ( <4000)
• FC > 90

Question 2

Sepsi

Answer 2

Aumento acuto del Sofa score a 2

è una disfunzione d’organo

Question 3

Sepsi grave

Answer 3

• PAS < 90
• PAM < 70
• Necessita e risponde a infusione di liquididi IV ( 30 ml/kg)
• aumento lattato sierico

Question 4

qSOFA

Answer 4

• PAS < 100
• FR > 22
• GLASCOW COMA SCORE < 15 ( se < di 8 richiedere intubazione oro tracheale)

Question 5

Shock settico

Answer 5

Necessario trattamento con inotropi positivi e/o vasopressori per mantenere la PAM soptra i 65mmhg.
Riscontriamo livelli di lattato sierico maggiori di 18mg/dl

Refrattario quando persistente da più di un’ora e non risponde né a liquidi ne a farmaci vasopressori

Question 6

Trattamento

Answer 6

Empiric antibiotic treatment: begin immediately after blood cultures have been drawn, preferably within 1 hour after recognition

Treat for MRSA until ruled out: vancomycin or linezolid/daptomycin in combination with either:
Piperacillin/tazobactam, cefepime, or carbapenems if Pseudomonas infection is likely
3rd generation cephalosporin (e.g., ceftriaxone or cefotaxime) if Pseudomonas infection is unlikely

Antifungal treatment in cases of documented fungemia (presence of a fungus in the bloodstream)